 | | Vol. 7.14 – 19 April, 2021 |
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| Scientists detected a focal, canonical hypomethylation phenotype that revealed considerable overlap with hypomethylated regions found in Dnmt3a-deficient mouse skin.
[Proceedings of the National Academy of Sciences of the United States of America] |
|  | | PUBLICATIONSRanked by the impact factor of the journal |
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| DERMAL STEM CELLS & TISSUE REGENERATION |
| | In monolayer-culture and living skin equivalent, IL-4/IL-13 increased the expression of full-length IL-33 in the nucleus of keratinocytes by activating the MEK/ERK signaling pathway, which is necessary for the inhibition of differentiation markers filaggrin, loricrin, keratin1, and keratin 10.
[Journal of Investigative Dermatology] |
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Investigators found that MyoD-induced trans-differentiation of fibroblasts to myoblasts promoted the expression of the ADP-ribosyltransferase ARTD1.
[iScience] |
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Researchers tested five functional cosmeceutical peptides on their individual and mixed activities to detect a suitable anti-aging and protective formula from their experiments.
[Skin Pharmacology and Physiology] |
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| A release and skin permeation study was carried out in vertical diffusion cells. The extraction procedure allowed quantifying high punicalagin content.
[Planta Medica] |
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| The investigation was planned utilizing SEM, histological, and furthermore cytokeratin immunohistochemical to give a full depiction of skin of three reptiles species; Chalcides ocellatus, Uromastyx aegyptia aegyptia, and Psammophis schokari aegyptia captured from Egypt with various ecological environment.
[Microscopy Research and Technique] |
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| Combinatorial nanostructured lipid carrier gel of 5-fluorouracil and resveratrol was formulated, optimized and characterized to enhance permeation in between epidermis and dermis layers of the skin to obtain a synergistic effect against skin cancer.
[European Journal of Pharmaceutics and Biopharmaceutics] |
| | Researchers found that apremilast could markedly ameliorate the pathological manifestations of systemic sclerosis, including skin dermal thickness, deposition of collagens, and increased expression of α-SMA..
[Acta Pharmacologica Sinica] |
| | Scientists investigated the role of GAS5 in wound healing in diabetic foot ulcer as well as the underlying mechanism.
[Laboratory Investigation] |
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| Scientists give an overview of the clinical picture, and characteristics of the patients as well as the diagnosis and therapy of eczema herpeticum.
[Allergy] |
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| The authors summarize the wide-ranging usages of H-1 antihistamines in dermatological fields other than itch and urticaria control.
[Dermatology and Therapy] |
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| DermTech, Inc. announced that the company has become a member of The Skin Cancer Foundation Corporate Council.
[DermTech, Inc. (BusinessWire, Inc.)] |
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| Morphogenesis, Inc., announced that the US FDA has granted orphan drug designation to the company’s lead candidate IFx-Hu2.0 for the treatment of stage IIB to stage IV melanoma.
[Morphogenesis, Inc.] |
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| October 26 – October 28
Virtual |
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| | Harvard Medical School – Boston, MA, United States |
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| | MD Anderson Cancer Center – Houston, Texas, United States |
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| | Howard Hughes Medical Institute – New York, New York, United States |
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| | The Wistar Institute – Philadelphia, Pennsylvania, United States |
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| | Mount Sinai Health System – New York, New York, United States |
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