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| Scientists demonstrated that Lgr6 marked a regionally restricted population of epidermal stem cells that interacted with nerves and specialized in wound re-epithelialization. [Cell Stem Cell] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| In vitro biophysical and cellular analyses demonstrated that cyclometalated iridium(III) metal complex 1a bound to Von Hippel-Lindau (VHL) and inhibited the VHL–hypoxia-inducible factor-1α (HIF)-1α interaction. [Nature Communications] |
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| Researchers studied transcriptome profiles of human nail units using polydactyly specimens. SPINK6 expression distinguished the nail-specific keratinocytes from epidermal keratinocytes. [Communications Biology] |
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| Investigators examined whether mineralocorticoid receptor antagonists could ameliorate glucocorticoid receptor-mediated skin barrier dysfunction in normal human epidermal keratinocytes, reconstructed human epidermis, and subjects under psychological stress. [Scientific Reports] |
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| Researchers used a previously developed 3D clinostat to simulate a microgravity environment and investigated whether physiological changes of the skin could be reproduced in a 3D in vitro setting. [NPJ Microgravity] |
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| Scientists found that high group 2 innate lymphoid cells (ILC2) infiltration in human melanoma was associated with a good clinical prognosis. ILC2s were critical producers of the cytokine granulocyte-macrophage colony-stimulating factor, which coordinated the recruitment and activation of eosinophils to enhance antitumor responses. [Nature Immunology] |
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| The authors identified a natural acidic formulation to reduce skin pigmentation. The metabolite propionic acid was the most abundant fatty acid in the filtrate from Pluronic F68 fermentation of Cutibacterium acnes and reduced the DOPA-positive melanocytes by significantly inhibiting cellular tyrosinase activity via binding to the free fatty acid receptor 2. [Scientific Reports] |
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| The effects of Talazoparib and Niraparib in combination with ionizing radiation on cell death, clonogenicity and cell cycle arrest were studied in healthy primary fibroblasts and primary melanoma cells. [Genes] |
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| Investigators assessed the effect of interleukin-7 signaling on T helper 17 responses in patients with primary cutaneous melanoma. [Melanoma Research] |
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| The authors summarize the recent research progress on the effects of non-coding RNAs (ncRNAs) on melanoma and attempt to elucidate the role of ncRNAs as molecular markers or potential targets will provide promising application perspectives of melanoma. [Molecular Therapy-Oncolytics] |
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| Kerecis, Inc. announced the release of Kerecis® Omega3 MicroGraft. The easy-to-use product is intact fish skin divided into fragments, which mold into wound beds. [Kerecis, Inc. (BusinessWire, Inc.)] |
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| Apyx Medical Corporation announced it has submitted a 510(k) premarket notification to the US FDA, which is intended to obtain a specific clinical indication for the use of Renuvion® in dermal resurfacing procedures. [Apyx Medical Corporation (BusinessWire, Inc.)] |
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| September 6 – 10, 2021 Virtual |
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| Ulsan National Institute of Science and Technology – Ulsan, South Korea |
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| University of Michigan – Ann Arbor, Michigan, United States |
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| Wellcome Trust Sanger Institute – Cambridge, England, United Kingdom |
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| University of Copenhagen – Copenhagen, Denmark |
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| National Institutes of Health – Bethesda, Maryland, United States |
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