 | | Vol. 7.35 – 4 October, 2021 |
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| The authors identified Nance-Horan Syndrome-like 1 protein as a direct binding partner of the Scar/WAVE complex, which co-localized at protruding lamellipodia.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Investigators found that following traumatic injury to ear pinnae, myofibroblasts appeared rapidly in both Acomys and mouse yet persisted only in mouse.
[Developmental Cell] |
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| Researchers grew and differentiated human keratinocytes within a microfluidic chip to construct an integrated epidermis-on-a-chip system, which was specially designed to integrate multi-culture units with integrated bubble removal structure.
[Lab On A Chip] |
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| Scientists analyzed dose–response relationships in the GARDskin assay to identify chemical-specific concentrations that were sufficient to induce a positive response in the assay.
[Scientific Reports] |
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| The authors demonstrated that the proliferation of keratinocytes and their secretion of cytokines and growth factors could be activated through appropriate electrical stimulation to benefit skin wound healing.
[Biomedical Materials] |
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| Researchers observed the effect of calcium silicate (CS) on human epidermal stem cells and investigated its possible mechanism. They explored the therapeutic effect of CS on wound healing and re-epithelialization.
[Burns & Trauma] |
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| Investigators used single-cell RNA-seq and assay for transposase-accessible chromatin which revealed reduced expression of cell adhesion and extracellular matrix genes in aged hair follicle-stem cells.
[Nature Aging] |
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| Scientists identified skin factors that mediated key events during the early interaction with Batrachochytrium dendrobatidis zoospores, and discovered a marker for host colonization.
[Nature Communications] |
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| Researchers identified type XI collagen α1 chain (COL11A1) mutations in 66 of 100 cutaneous squamous cell carcinoma concentrated in a triple helical region known to produce trans-dominant collagen.
[Oncogene] |
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| Scientists demonstrated that physapubenolide (PB) inhibited cell proliferation and migration in melanoma cells by inducing cell apoptosis. They explored the mechanism underlying the anticancer effects of PB through an in silico target prediction study.
[Acta Pharmaceutica Sinica B] |
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| The authors discuss how intravital microscopy can reveal regenerative and pathological responses to implants, including wound healing and graft integration, which depend on the time-controlled activation of macrophages and early neovascularization, and adverse reactions.
[Nature Reviews Materials] |
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| Nanyang Technological University and L’Oréal Singapore launched a joint laboratory to conduct research on the microbiome of our skin and scalp.
[Nanyang Technological University] |
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| Bristol Myers Squibb announced Marketing Authorization Application (MAA) validation for the LAG-3-blocking antibody relatlimab and nivolumab fixed-dose combination for first-line treatment of adult and pediatric patients with advanced (unresectable or metastatic) melanoma.
[Bristol Myers Squibb] |
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| November 8 – 10, 2021
Virtual |
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| | Technical University of Denmark – Lyngby, Denmark |
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| | The University of New Mexico – Albuquerque, New Mexico, United States |
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| | Novo Nordisk – Indianapolis, Indiana, United States |
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| | University of Minnesota – Austin, Minnesota, United States |
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| | University of Pennsylvania – Philadelphia, Pennsylvania, United States |
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