| Vol. 8.11 – 4 April, 2022 |
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| Researchers demonstrated a multifunctional chitosan/silver/tannic acid cryogel based on an economic method to block acute hemorrhage and promote wound healing. [International Journal of Biological Macromolecules] |
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PUBLICATIONSRanked by the impact factor of the journal |
| DERMAL STEM CELLS & TISSUE REGENERATION |
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| A 91% cell viability result in the MTT assay with human dermal fibroblast cells confirmed the noncytotoxicity of the membrane. Tripeptides produced after the thermolysin-based hydrolysis of zein caused inhibition of TGF β1 expression and thus increased fibroblast and collagen production. [ACS Applied Bio Materials] |
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| The skin samples of Liaoning cashmere goats during the growing period were collected, performed tandem mass tag method, and identified 117 differentially expressed proteins in course type and fine type. [Functional & integrative Genomics] |
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| Though nobiletin limited UVB-irradiated human keratinocytes from undergoing cell death, researchers found that this enhanced survival was not associated with increased nucleotide excision repair or XPA expression. Instead, nobiletin reduced initial UV photoproduct formation and promoted a G1 cell cycle arrest. [Photochemistry and Photobiology] |
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| Scientist sequenced the DNA of cutaneous and acral melanomas from a large cohort of human patients and found a specific enrichment for BRAF mutations in cutaneous melanoma and enrichment for CRKL amplifications in acral melanoma. [Nature] |
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| The authors found that cataract, alopecia, oral mucosal disorder, and psoriasis-like syndrome was caused by an autosomal recessive defect in the mitochondrial membrane-bound transcription factor peptidase/site-1 protease (MBTPS1, S1P). [EMBO Molecular Medicine] |
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| Researchers determined the anti-fibrotic efficacy and potential mechanisms of bromodomain and extra-terminal domain proteins inhibition in systemic sclerosis. [JCI Insight] |
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| Scientists analyzed the expression of α7nAchR in human and mouse psoriatic skin tissue. In vivo, PNU-282987 or Methyllycaconitine, a specific agonist or antagonist of α7nAchR, were administered to imiquimod-induced psoriatic mouse models. [Cell Death Discovery] |
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| Researchers identified PPP6C, a serine/threonine phosphatase, as a key regulator of MITF in melanoma. [Scientific Reports] |
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| The authors focuse on a deeper understanding of the possible role of proliferator-activated receptor γ (PPARγ) in the pathogenesis of psoriasis and the potential of PPARγ agonist to improve the treatment of psoriasis. [Molecular and Cellular Biochemistry] |
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| MedX Health Corp. announced a Memorandum of Understanding and the launch of a new commercialization pilot project with Health Partners Limited, a health, treatment and primary care services company in the United Kingdom. [MedX Health Corp.] |
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| 13 – 14 June 2022 London, England, United Kingdom |
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| Wellcome Sanger Institute – Cambridge, England, United Kingdom |
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| In4Derm Ltd – Dundee, Scotland, United Kingdom |
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| Wellcome Sanger Institute – Cambridge, England, United Kingdom |
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| University of Southern Denmark – Odense M, Denmark |
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| Columbia University Medical Center – New York City, New York, United States |
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