 | | Vol. 8.14 – 25 April, 2022 |
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| Researchers found that the cell-to-cell variations of specific lipid metabolic pathways contributed to the establishment of cell states involved in the organization of skin architecture.
[Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
| | DERMAL STEM CELLS & TISSUE REGENERATION |
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| Investigators reported the development and utilization of mRNA nanosensors that were topically applied on cutaneous wounds revealed the healing status through targeted and semi-quantitative examination of the mRNA biomarkers in skin cells.
[Advanced Science] |
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| The authors investigated the expression of CXCL12 and its receptor, CXCR4, in the vicinity of hair follicles and their effect on hair growth.
[Biomedicine & Pharmacotherapy] |
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| Scientists determined the effects of hexetidine, povidone-iodine, undecylenamidopropyl-betaine/polyhexanide, chlorhexidine, disodium eosin, and hydrogen peroxide, on human skin fibroblasts.
[Clinical and Experimental Dermatology] |
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| Researchers probed the action of Portuguese propolis extracts on skin cells, provided mechanistic insights into its mode of action and preliminarily assesed its applicability as a skin repair ingredient.
[International Journal of Cosmetic Science] |
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| Investigators showed that the nuclear and micronuclear membranes of melanoma cells were frequently ruptured by macroscopic mechanical stress on the plantar surface due to weight-bearing activities.
[Nature Communications] |
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| Ten cell lines and two mouse models were used for assessing the in vitro and in vivo anti-melanoma effects of luteolin.
[Biochemical Pharmacology] |
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| Reversal of cancer symptoms in melanoma associated with vemurafenib resistance was driven by reactivation of MAPK and PI3K/Akt signaling pathways.
[Saudi Journal of Biological Sciences] |
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| Scientists found that 2-methoxyestradiol significantly affected the proliferation, migration, apoptosis, and cell cycle of melanoma in vitro.
[Immunopharmacology and Immunotoxicology] |
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| The authors review and discuss latest discoveries related to the skin odorant receptors (ORs) activated by flavor compounds, their impacts on skin health and disease, odorant ligands interacting with ORs exerting specific biological effects, and the mechanisms involved.
[Critical Reviews in Food Science and Nutrition] |
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| Investigators examine possible beneficial or detrimental effects of treating established cancer with vitamin D3.
[Pigment Cell & Melanoma Research] |
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| The authors highlight the advent of nanomaterial-based constructs for wound healing, especially those that are being evaluated in clinical settings.
[ACS Applied Bio Materials] |
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| Sol-Gel Technologies, Ltd. announced the FDA approval of its drug product, EPSOLAY®, a proprietary cream formulation of benzoyl peroxide, 5%, for the treatment of inflammatory lesions of rosacea in adults.
[Sol-Gel Technologies Ltd.] |
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| Quoin Pharmaceuticals Ltd. announced that it has received FDA clearance to initiate clinical testing for its Investigational New Drug application for QRX003, the Company’s investigational product for Netherton Syndrome.
[Quoin Pharmaceuticals, Inc.] |
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| June 21 – June 24
San Francisco, California, United States |
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| | Fred Hutchinson Cancer Center – Seattle, Washington, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | City of Hope – Duarte, California, United States |
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| | Helmholtz Munich – München, Germany |
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