 | | Vol. 5.24 – 06 July, 2020 |
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| Neovascularization and angiogenesis were assessed by in vivo Matrigel plug assay and in vitro tube formation assay, respectively.
[Arthritis & Rheumatology] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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Investigators designed a novel angiogenic microparticle comprising Alaska pollock-derived gelatin modified with a dodecyl group to stimulate endogenous VEGF secretion.
[NPG Asia Materials] |
| | The effects of CCL20 on endothelial cell migration and tumor-associated vascularisation were comprehensively analysed with chemotaxis assays in vitro and in CCR6-deficient mice in vivo.
[British Journal of Cancer] |
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| Researchers found that β-catenin depleted HUVEC stimulated with pharmacological activators of endothelial NO synthase (eNOS) showed a reduction in eNOS phosphorylation as well as reduced intracellular cyclic guanosine monophosphate levels compared to control cells in static cultures.
[Cell Death & Disease] |
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| Overexpression of ANRIL transcript NR_003529 increased monocyte adhesion to endothelial cells (ECs) and transendothelial monocyte migration (TEM), whereas knockdown of NR_003529 expression reduced monocyte adhesion to ECs and TEM.
[RNA Biology] |
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| An in vitro model of endothelial damage mediated by p-cresol (PcEMV) was proposed to evaluate the functional effect of PcEMV on the endothelial repair process carried out by endothelial cells and microRNA that could be involved in this process.
[Scientific Reports] |
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| The histological and molecular characterization was conducted on anatomically-matched skin and fat biopsies as well as serum samples from eleven lipedema and ten BMI-matched healthy patients.
[Scientific Reports] |
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| Poly‐(HEMA‐co‐NIPAM) solution incorporated with copper ions not only exhibited excellent antibacterial properties, but also expedited wound closure and facilitated tissue angiogenesis.
[Journal of Biomedical Materials Research Part B-Applied Biomaterials] |
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Investigators showed that Zeb1 is an important factor promoting vascular endothelial cell (EC) proliferation and corneal neovascularization (NV); and a couple of small molecule inhibitors can evict Ctbp from the Zeb1–Ctbp complex, thereby reducing EC Zeb1 expression, proliferation, and corneal NV.
[Communications Biology] |
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| The authors focus on some recent advances in understanding endothelial cell behavior in health and disease and identify novel molecular players and concepts that could eventually be considered for therapeutic targeting.
[Circulation Research] |
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| Scientists introduced a 3D microfluidic platform that juxtaposes a human mammary duct in proximity to a perfused endothelial vessel.
[Nature Communications] |
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| The authors summarize how extracellular matrix (ECM) dynamics control vascular remodeling, and further indicate potential diagnostic biomarkers and therapeutic targets in the ECM for corresponding vascular diseases.
[American Journal of Physiology-Cell Physiology] |
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| Adverum Biotechnologies, Inc. announced the completion of patient dosing in Cohort 4 of OPTIC, a Phase I clinical trial, assessing a single intravitreal injection of ADVM-022 in patients with wet age-related macular degeneration (AMD).
[Adverum Biotechnologies] |
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| In mid-March, as businesses and universities across Europe were shutting down in a bid to slow the COVID-19 pandemic, three longtime friends were talking about how they wished they could do something to combat the disease.
[The Scientist] |
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| Life sciences professors and other staff make contingency plans for more coronavirus-related disruptions in the coming school year.
[The Scientist] |
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| October 20 – October 21
Virtual |
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| | Universitätsklinikum Bonn – Bonn, Germany |
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| | The University of Texas Health Science Center at Houston – Houston, Texas, United States |
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| | Queen’s University Belfast – Belfast, United Kingdom |
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| | The Brigham and Women’s Hospital – Boston, Massachusetts, United States |
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| | University of California, San Diego – San Diego, California, United States |
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