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| Within the vasculature, Prdm16 expression was strictly expressed by arterial endothelial and smooth muscle cells.
[Circulation Research] |
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|
 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers addressed mechanisms of generation of a population of S1PR1+ endothelial cells and their pivotal role in restoring endothelial integrity.
[Circulation Research] |
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| Through transcriptional analysis of murine dermal lymphatic endothelial cells, scientists identified Foxp2, a member of the FOXP family of transcription factors implicated in speech development, as a collecting vessel signature gene.
[EMBO Journal] |
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| Proteomic changes occurred within five min of intracarotid arterial hyperosmolar mannitol (ICAHM) infusion and returned to baseline by 96 hours. Transcriptomic analyses following ICAHM blood–brain barrier disruption further supported an sterile inflammatory response.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Researchers showed that endothelial tip cells use dactylopodia as the main cellular protrusion for invasion into nonvascular extracellular matrix. They showed that dactylopodia and filopodia protrusions were balanced by myosin IIA and actin-related protein 2/3 activity.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| The authors used gene‐modified mice with endothelial cell‐specific overexpression of human IGF‐1R and their wild‐type littermates.
[EMBO Reports] |
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| Using a vascularised lung‐on‐chip model, scientists found that infection of alveolar epithelial cells led to limited apical release of virions, consistent with reports of monoculture infection.
[EMBO Reports] |
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| Researchers evaluated whether angiogenic imbalance affected the expression and secretion of inhibitory complement factor H in endothelial cells, resulting in complement activation and systemic vascular endothelial dysfunction.
[Journal of Reproductive Immunology] |
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| Investigators hypothesized that the perivascular properties of human umbilical cord perivascular cells could reduce vascular dysfunction after modelled traumatic brain injury by preserving the pericyte-endothelial interactions.
[Journal of Neurotrauma] |
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| The authors measured total cell free (cf)DNA by targeting ALU repetitive sequences and measured endothelial-derived cfDNA by methylation-specific qPCR targeting an endothelium-unique unmethylated CDH5 DNA region.
[PLoS One] |
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| Scientists describe the relationship between plasma high density lipoprotein and vascular function during healthy pregnancy and details how this is lost in pre-eclampsia, a disorder of pregnancy associated with widespread endothelial dysfunction.
[Biochimica et Biophysica Acta – Molecular and Cell Biology of Lipids] |
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| D&D Pharmatech, Inc. announced it has entered into a sponsored research agreement with Yale University relating to optimization of two novel approaches that allow immune system cells and drug molecules to bypass the blood-brain barrier for the treatment of brain cancer and other disorders.
[D&D Pharmatech, Inc. (Business Wire, Inc.))] |
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| June 9 – 17, 2021
Virtual |
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| | Stanford University – Stanford, California, United States |
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| | Aarhus University – Copenhagen, Denmark |
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| | LSU Health Science Center – Shreveport, Louisianam United States |
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| | Icahn School of Medicine at Mount Sinai – New York, New York, United States |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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