 | | Vol. 6.33 – 27 September, 2021 |
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| In human endothelial cells, a striking correlation was observed between the degree of endothelial cell activation as reflected by intracellular adhesion molecule 1, isoLG-adduct accumulation and intracellular GAS6 levels.
[Circulation Research] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The authors found that Fli1 governed vascular morphogenesis by regulating endothelial potential by inversely regulating endothelial versus myogenic programs in myogenic progenitor cells.
[Circulation Research] |
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| Scientists identified integrin α5β1 as an endothelial cell receptor for angiogenic factor and G-patch and FHA [Forkhead-associated] domain 1 (AGGF1) and a novel AGGF1-mediated signaling pathway of α5β1-FAK-Src-AKT for angiogenesis.
[Arteriosclerosis Thrombosis & Vascular Biology] |
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| Researchers determined that macrophage-derived exosomes could augment the angiogenic activities of spinal cord microvascular endothelial cells in vitro.
[Acta Biomaterialia] |
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| Investigators applied a novel bioengineering approach to generate human blood-brain barrier organoids by the self-assembly of astrocytes, pericytes and brain endothelial cells with unprecedented throughput and reproducibility using micro patterned hydrogels.
[Fluids and Barriers of the CNS] |
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| To study and compare the development of vascular networks formed during angiogenesis and vasculogenic mimicry a number of in vitro assays were utilized.
[Communications Biology] |
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| Scientists built a lymphatic vessel-on-chip by fabricating a microfluidic device that included a hollow microchannel embedded in 3D hydrogel.
[Microcirculation] |
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| The authors analyzed the endothelial function, molecular signature, and mitochondrial profile of chronic thromboembolic pulmonary hypertension (CTEPH)-derived endothelial cells to better understand the pathophysiological mechanisms of endothelial dysfunction behind CTEPH.
[Scientific Reports] |
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Tramadol upregulated the expression of oxidative stress and inflammatory markers in mice heart and aorta, whereas downregulated endothelial nitric oxide synthase enzyme expression.
[Scientific Reports] |
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| Scientists discuss responses of the epithelium that promote airway immunopathology, with a focus on miRNAs that contribute to the breakdown of essential epithelial functions.
[Immunological Reviews] |
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| BetterLife Pharma, Inc. announced that its wholly owned subsidiary, Altum Pharmaceuticals Inc., and Pontificia Universidad Católica de Chile have enrolled the first patient in the Phase I portion of the Phase I-II randomized placebo controlled in COVID-19 patients.
[BetterLife Pharma, Inc. (GlobeNewswire, Inc.)] |
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| The Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at UCLA has been awarded $5 million by the California Institute for Regenerative Medicine, the state’s stem cell agency, to train young scientists and physicians to become leaders in the stem cell and regenerative medicine field.
[University of California] |
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| November 6 – 7, 2021
Waterville Valley, New Hampshire, United States |
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| The University of New Mexico – Albuquerque, New Mexico, United State |
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| | The University of New Mexico – Albuquerque, New Mexico, United States |
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| | The University of Texas MD Anderson Cancer Center – Houston, Texas, United States |
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| | University of Southern California – Los Angeles, California, United States |
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| | University of Cambridge – Cambridge, England, United Kingdom |
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