 | | Vol. 7.08 – 14 March, 2022 |
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| Researchers demonstrated that PROCR-219Gly increased plasma levels of protein C through endothelial protein C receptor ectodomain shedding in endothelial cells, attenuating leukocyte-endothelial cell adhesion and vascular inflammation.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Based on proteomic profiling of angiogenic endothelial components, researchers reported βIV-spectrin, a non-erythrocytic cytoskeletal protein, as a critical regulator of sprouting angiogenesis.
[Nature Communications] |
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| Investigators demonstrated that secondary vascular field cells participated in vascular recovery after chemical ablation of vascular endothelial cells.
[Developmental Cell] |
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| Researchers investigated the role of RTN4/Nogo-A in mediating macroautophagy/autophagy and angiogenesis in the thalamus following middle cerebral artery occlusion.
[Autophagy] |
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| Scientists reported that cardiac stress-induced differential microRNA content, with miR-200c-3p being one of the most enriched, in cardiomyocyte-derived extracellular vesicles mediated functional crosstalk with endothelial cells.
[Molecular Therapy] |
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| In human pulmonary aortic endothelial cells,lipopolysaccharide-induced decreased in the amounts of endothelial nitric oxide synthase, thrombomodulin, and vascular endothelial–cadherin, which was blocked by treatment with UNC2250.
[Science Signaling] |
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| Macrophage-derived VEGF activated CD34+ progenitor cells within the adventitial vasculogenic zone to differentiate into CD31+ endothelial cells.
[Cell Death & Disease] |
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| Researchers investigated whether plasma Tie2 could predict response and progression cross-tumor for generic vascular endothelial growth factor inhibitors (VEGFi) treatment.
[ESMO Open] |
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| The authors investigated the role of histone deacetylase 11 (HDAC11) in vascular endothelial cell pyroptosis and its molecular mechanism.
[Cell Death Discovery] |
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| Scientists reported the identification of a novel adenosine monophosphate-activated protein kinase (AMPK) modulator, the indolic derivative IND6, which showed affinity for AMPKα1β1γ1, the primary AMPK isoform in human EA.Hy926 endothelial cells.
[Scientific Reports] |
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| The aim of this review is to summarize and provide an overview of the role of swiprosin-1 in pathophysiological conditions of cancers, cardiovascular diseases, diabetic nephropathy, neuropsychiatric diseases, and in the process of inflammation, immune response, and inflammatory diseases.
[Life Sciences] |
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| Samsung Bioepis Co., Ltd. and Biogen Canada Inc. announced that Health Canada has approved BYOOVIZ™ a biosimilar referencing LUCENTIS® for the treatment of neovascular age-related macular degeneration; visual impairment due to diabetic macular edema.
[Samsung Bioepis Co., Ltd.] |
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| March 20 – March 25, 2022
Vienna, Austria |
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| Babraham Institute – Cambridgeshire, England, United Kingdom |
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| | Johns Hopkins School of Medicine – Saint Petersburg, Florida, United States |
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| | The University of Tennessee Health Science Center – Memphis, Tennessee, United States |
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| Yale University – New Haven, Connecticut, United States |
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| | Columbia University – New York, New York, United States |
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