| Vol. 7.25 – 18 July, 2022 |
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| Scientists assessed the ability of circulating host markers of immune and endothelial activation quantified at presentation, relative to currently used clinical measures of disease severity, to identify children with pneumonia who are at risk of death. [PLoS Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Cultured endothelial cells endocytosed cancer cell-derived extracellular vesicles, resulting in cytoskeletal rearrangement and low expression of the junction proteins cadherin and CD31, and formed large intercellular gaps allowing the transendothelial migration of cancer cells. [Cancer Letters] |
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| Endothelial progenitor cells were isolated from rat bone marrow and their morphology and function were studied. [Frontiers in Pharmacology] |
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| Investigators found that overexpression of ANGPTL4 in HUVECs enhanced cell proliferation and clone-forming ability in vitro, whereas knockdown of ANGPTL4 resulted in the opposite. [Cellular Signalling] |
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| The authors found that platycodin D at noncytotoxic concentrations inhibited VEGF-induced proliferation, adhesion to the extracellular matrix proteins fibronectin and vitronectin, chemotactic motility, and tube formation of HUVECs. [American Journal of Chinese Medicine] |
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| Researchers determined therapeutic potential of apolipoprotein A1 for endothelial cell repair under a pathological condition reminiscent of amyotrophic lateral sclerosis (ALS). [eNeuro] |
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| The authors summarize how endothelial cells adjust to injury and how this dynamic response contributes to repair and regeneration. [Basic Research in Cardiology] |
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| Multiple in vitro models of the blood-brain barrier are available to investigate the mechanisms underlying the pathogenesis of cerebral malaria and other diseases. [Disease Models & Mechanisms] |
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| Carl Zeiss Meditec and Precise Bio announced that the companies have entered into a partnership to develop and commercialize fabricated corneal tissue for transplants in patients that require endothelial keratoplasty and natural lenticule transplants for treating keratoconus and vision correction. [Precise Bio (Cision US, Inc.)] |
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| December 8 – 10, 2022 Los Angeles, California, United States |
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| University of Lausanne – Lausanne, Vaud, Switzerland |
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| Genentech, Inc. – South San Francisco, California, United States |
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| King’s College London – London, England, United Kingdom |
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| LMU Klinikum – München, Germany |
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| University Hospital of Muenster – Münster, Germany |
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