TOP STORY Researcher Discovers Key Mechanism for Transforming Adult Cells Researchers have discovered that so-called “grim-reaper” caspase genes are the gatekeepers that can open the door to allow differentiated adult cells to regress to undifferentiated induced pluripotent stem cells. [Press release from the University of Colorado Denver discussing online prepublication in Cell Stem Cell]
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SCIENCE NEWS Stem Cell Model for Long-QT Syndrome May Spark New Avenues for Heart Research Pluripotent stem cells, derived from skin fibroblasts of two relatives with familial long-QT syndrome and induced to differentiate into cardiac myocytes, exhibited the electrophysiologic traits of the disorder, showing for the first time that stem cell models “can recapitulate aspects of genetic cardiac diseases.” [Press release from Internal Medicine News discussing online prepublication in the New England Journal of Medicine] ‘Firefly’ Stem Cells May Repair Damaged Hearts Stem cells that glow like fireflies could someday help doctors heal damaged hearts without cutting into patients’ chests. The “firefly” stem cells, engineered with the same enzyme that makes fireflies glow, become brighter and brighter as they develop into healthy heart muscle, allowing doctors to track whether and where the stem cells are working. [Press release from the University of Central Florida discussing online prepublication in Stem Cells and Development]
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INDUSTRY NEWS STEMSOFT Connect — A Simplified Solution to a Complex Problem STEMSOFT is pleased to announce the release of their new standard interfaces, STEMSOFT Connect™. STEMSOFT Connect offers standard interface tools that easily connect commonly used applications and devices to STEMSOFT’s applications. [STEMSOFT Software Inc. Press Release] Cell Cure Neurosciences Ltd., a Subsidiary of BioTime, Inc. and Hadasit Bio Holdings Ltd., Enters into an Exclusive License Option Agreement with Teva Pharmaceutical Industries Ltd. to Develop and Market OpRegen™ for the Treatment of Age-Related Macular Degeneration BioTime, Inc., Cell Cure Neurosciences Ltd., and Hadasit Bio-Holdings Ltd. jointly announced that Cell Cure and Teva Pharmaceutical Industries Ltd. have entered into an exclusive license option agreement to develop and commercialize Cell Cure’s OpRegen™ product for the treatment of age-related macular degeneration. OpRegen™ is a proprietary formulation of embryonic stem cell-derived retinal pigment epithelial cells designed by Cell Cure. [BioTime, Inc. Press Release] Regional Government of Andalusia, Spain and California Announce International Collaboration to Advance Stem Cell Research Toward Cures The California Institute for Regenerative Medicine and the Andalusian Initiative for Advanced Therapies announced an international collaboration on stem cell research. [California Institute for Regenerative Medicine Press Release] Genzyme Board Unanimously Rejects Sanofi-Aventis Tender Offer Genzyme Corporation announced that its board of directors has voted unanimously to reject the unsolicited $69.00 per share tender offer from Sanofi-Aventis, and the board recommends that Genzyme shareholders not tender their shares to Sanofi-Aventis pursuant to the offer. [Genzyme Corporation Press Release] American Cancer Society Awards New Research and Training Grants The American Cancer Society has awarded 94 national research and training grants totaling $46,633,000 to 70 institutions nationwide in the first of two grants cycles for 2011. [American Cancer Society Press Release] Geron Initiates Clinical Trial of Human Embryonic Stem Cell-Based Therapy Geron Corporation announced the enrollment of the first patient in the company’s clinical trial of human embryonic stem cell-derived oligodendrocyte progenitor cells, GRNOPC1. [Geron Corporation Press Release] Embryonic Stem Cell Research Receives Widespread Support from Americans A large majority of Americans across various demographic groups agree that scientists should be able to use stem cells for biomedical research, according to a recent Harris Interactive/HealthDay poll. [Harris Interactive Press Release] Shrinking U.S. Biotechnology Sector Lost 25% of Companies in Past 3 Years One hundred publicly traded biotechnology companies in the U.S. have been acquired or ceased operations since the end of 2007, a 25 percent drop in the number of active companies, a report said. [Bloomberg]
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POLICY NEWS Governor Doyle Announces State Has Filed Motion to Join Stem Cell Funding Amicus Brief Governor Jim Doyle announced the state has filed a motion in the U.S. District Court for the District of Columbia seeking permission to join an amicus brief in Sherley v. Sebelius, a legal case challenging the National Institutes of Health’s embryonic stem cell research guidelines. [Office of the Governor of Wisconsin, United States] NIH Announces New Program to Accelerate Research Independence The National Institutes of Health intends to invest approximately $60 million over the next five years in the NIH Director’s Early Independence Award program to help junior investigators leapfrog over traditional post-doctoral training and move into independent academic positions at U.S. institutions, directly upon completion of their graduate research degrees. [National Institutes of Health, United States] FDA’s $25 Million Pitch for Improving Drug Regulation The U.S. Food and Drug Administration (FDA) is pressing for a big funding boost for “regulatory science”—research that can help it evaluate new treatments better and faster. [Food and Drug Administration, United States] FDA to Push for More Investment in Science Health regulators plan to spend millions of dollars to step up their scientific prowess in a move that officials say will help quickly get new treatments to patients and protect the public against possible health threats. [Food and Drug Administration, United States] Plan to Develop a Genetic Testing Registry at the National Institutes of Health; Public Meeting; Request for Comments (FR Doc. 2010-25411) [National Institutes of Health, United States] Proposed Collection; Comment Request; National Evaluation of the Clinical and Translational Science Awards (CTSA) Initiative (FR Doc. 2010-25589) [Department of Health and Human Services, United States] Agency Information Collection Request. 30-Day Public Comment Request (FR Doc. 2010-25587) [Department of Health and Human Services, United States] National Human Genome Research Institute; Notice of Closed Meeting (FR Doc. 2010-25634) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-25595) [National Institutes of Health, United States] Center for Scientific Review; Notice of Closed Meetings (FR Doc. 2010-25597) [National Institutes of Health, United States] Center for Scientific Review; Amended Notice of Meeting (FR Doc. 2010-25598) [National Institutes of Health, United States] Center for Scientific Review; Amended Notice of Meeting (FR Doc. 2010-25601) [National Institutes of Health, United States] National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-25636) [National Institutes of Health, United States] National Cancer Institute; Notice of Closed Meeting (FR Doc. 2010-25640) [National Institutes of Health, United States] National Center for Research Resources; Notice of Closed Meeting (FR Doc. 2010-25176) [National Institutes of Health, United States] National Institute of Biomedical Imaging and Bioengineering; Notice of Closed Meeting (FR Doc. 2010-25172) [National Institutes of Health, United States]
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EVENTS Stem Cells and Regenerative Medicine – New Solutions to Old Problems October 18-20, 2010 San Antonio, United States European Society of Gene and Cell Therapy (ESGCT) 18th Annual Congress October 22-25, 2010 Milan, Italy World Stem Cells & Regenerative Medicine Congress Asia 2010 October 26-28, 2010 Seoul, Korea Fraunhofer Life Science Symposium Leipzig 2010 October 29-30, 2010 Leipzig, Germany NEW 5th UK Cancer Stem Cell Symposium November 2, 2010 London, United Kingdom Stem Cell Society Singapore Symposium 2010: Translating Science to Therapy November 2-3, 2010 Singapore BioMalaysia 2010 Conference and Exhibition November 1-3, 2010 Kuala Lumpur, Malaysia Select Biosciences 2nd International Forum on Stem Cells (2010 IFSC) November 12-13, 2010 Tianjin, China The 16th International Conference of the International Society of Differentiation: From Stem Cells to Organisms November 15-18, 2010 Nara, Japan 8th Annual Commercial Translation of Regenerative Medicine Conference November 18-19, 2010 London, United Kingdom Stem Cell Network’s 10th Annual Scientific Meeting November 22-24, 2010 Calgary, Alberta Tissue Engineering & Regenerative Medicine International Society – North America (TERMIS-NA) 2010 Annual Conference December 5-8, 2010 Orlando, United States NEW 5th Annual Stem Cell Meeting on the Mesa December 7, 2010 La Jolla, United States Biotech Showcase 2011 January 10-12, 2011 San Francisco, USA Select Biosciences 5th Annual Stem Cells and Regenerative Medicine World Congress January 24-25, 2011 San Diego, United States Keystone Symposia-Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States Molecular Medicine Tri-Conference – Stem Cells: Revolutionizing Regenerative Medicine and Personalized Therapy 2011 February 23-25, 2011 San Francisco, United States American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer March 3-6, 2011 Vancouver, Canada Stem Cells, Cancer and Metastasis (C4) March 6-11, 2011 Dillon, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
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