 | | Vol. 11.25 – 2 July, 2020 |
| |
|
|
| Scientists used biodegradable polymer scaffolds seeded with autologous cells to restore uterine structure and function in rabbits. Rabbits underwent a subtotal uterine excision and were reconstructed with autologous cell-seeded constructs, with nonseeded scaffolds or by suturing.
[Nature Biotechnology] |
|  | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| The authors showed that tumor vascular function as well as pericyte coverage was significantly impaired in mice with conditional knockout of platelet-derived growth factor (PDGFB) in platelets.
[Cancer Research] |
|
|
|
| Investigators presented a hydrogel-based platform to control cell shape in three dimensions by using sequentially formed hybrid hydrogels consisting of collagen and alginate.
[NPG Asia Materials] |
|
|
|
| Researchers showed that constitutive and early loss of the epigenetic regulator, TET2, when combined with constitutive activation of FLT3, results in transformation of chronic myelomonocytic leukemia-like or myeloproliferative neoplasm-like phenotype to acute myeloid leukemia, which is more pronounced in double-mutant mice relative to mice carrying mutations in single genes.
[Stem Cell Reports] |
|
|
|
| The effects of CCL20 on endothelial cell migration and tumor-associated vascularization were comprehensively analyzed with chemotaxis assays in vitro and in CCR6-deficient mice in vivo.
[British Journal of Cancer] |
|
|
|
| The mRNA expression level of heparan sulfate proteoglycan 2 (HSPG2) in bone marrow mononuclear cells and CD34+ hematopoietic stem/progenitor cells obtained from enrolled participants and human leukemic cell lines was detected by RT-qPCR.
[Cell Death & Disease] |
|
|
|
| Scientists introduced a collagen-based 3D matrix to embed Raw264.7 cell line and primary rat bone marrow-derived macrophages.
[Scientific Reports] |
|
|
|
| Investigators developed pre-innervated tissue-engineered muscle comprised of long aligned networks of spinal motor neurons and skeletal myocytes on aligned nanofibrous scaffolds.
[Communications Biology] |
|
|
|
|
| Scientists provide current and futures perspectives on different approaches to conjunctival fibrosis following glaucoma surgery and highlights the challenges faced in implementing these therapies with maximal effect and minimal side effects.
[Eye] |
|
|
|
|
| AiViva Biopharma Inc., has announced completion of its first Phase I/IIa study evaluating AIV001 in dermal scarring. A total of 16 subjects who were scheduled to undergo abdominoplasty were enrolled and completed in one of the four double-blind dose escalation or open label cohorts.
[AiViva BioPharma] |
|
|
|
| The UK government plans to set up an “office for talent” to oversee visas and make it easier to attract top scientists after Brexit, according to an R&D road map.
[ScienceInsider] |
|
|
|
| Academics in Hong Kong are facing new worries after the mainland government abruptly imposed a controversial new security law that critics say could infringe on human rights and chill academic freedom.
[ScienceInsider] |
|
|
|
| Life sciences professors and other staff make contingency plans for more coronavirus-related disruptions in the coming school year.
[The Scientist] |
|
|
|
|
|
|
|
| | Max Planck Institute for Medical Research – Heidelberg, Germany | |
|
|
|
| | Drexel University – Philadelphia, Pennsylvania, United States |
|
|
|
| | University of Pittsburgh – Pittsburgh, Pennsylvania, United States |
|
|
|
| | The University of Washington – Seattle, Washington, United States |
|
|
|
| | Icahn School of Medicine at Mount Sinai – New York City, New York, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
