 | | Vol. 12.08 – 4 March, 2021 |
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| Scientists provided evidence that cardiomyocytes are infected in patients with COVID-19 myocarditis and are susceptible to severe acute respiratory syndrome coronavirus 2.
[Journal of the American College of Cardiology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators performed transcriptional profiling of tendon developmental processes to show that the ECM-associated protein periostin contributes to the maintenance of tendon stem/progenitor cell functions and promotes tendon regeneration.
[Nature Communications] |
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| The authors identified a critical requirement of B-plexin transmembrane receptors in the response to crowding-induced mechanical forces during embryonic skin development.
[Nature Communications] |
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| Using a novel human prostate stem cell antigen (PSCA) knock-in immunocompetent mouse model, researchers evaluated safety and therapeutic efficacy of PSCA-chimeric antigen receptor (CAR) T cells.
[Molecular Therapy] |
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| Researchers report that β-arrestin1 links the integrin-linked kinase (ILK)/βPIX complex to activate Rac3 GTPase, acting as a central node in the adhesion-based ECM sensing and degradation.
[Cell Reports] |
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| Designing a system that mimics natural environmental signals, which many spirochetes face during their infectious cycle, the authors observed that a subset of their surface proteins, particularly Decorin binding protein A/B, could strongly enhance the motility of spirochetes in the ECM of the host.
[Communications Biology] |
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| Researchers applied core–shell bioprinting to establish tailored 3D co-culture models for hepatocytes. The bioinks were specifically functionalized with natural matrix components and used to co-print fibroblasts and hepatocytes in a spatially defined, coaxial manner.
[Scientific Reports] |
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| Scientists investigated the effects of hypoxia on collagen production in human gingival fibroblasts and human periodontal ligament cells.
[Journal of Periodontology] |
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| The authors developed a 3D culture platform that mimics the metastatic tumor ECM to effectively increase cancer stem cell (CSC) population in vitro and allow CSC analysis.
[Biomedical Materials] |
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| Scientists improved and simplified the preparation of polyacrylamide gels using an economical crosslinker, N-hydroxysuccinimide-acrylamide ester, to enable increased stability in protein coating.
[Frontiers in Materials] |
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| The authors summarize the most recent literature characterizing clinical rheumatoid arthritis cachexia and links these features to the roles of and complex communication between multiple cellular contributors in the muscle niche, highlighting the importance of a targeted approach to therapeutic intervention.
[Journal of Biomedical Science] |
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| Novadip Biosciences announced that the FDA has approved the company’s Investigational New Drug (IND) application for its autologous cell therapy product NVD‑003 for the treatment of Congenital Pseudarthrosis of the Tibia.
[Novadip Biosciences] |
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| May 19 – 21, 2021
Virtual |
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| | University of Maryland School of Medicine – Baltimore, Maryland, United States |
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| | The Francis Crick Institute – London, England, United Kingdom |
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| | University of Southern Denmark – Odense M, Denmark |
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| | The University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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| | Merck Sharp and Dohme Limited – London, England, United Kingdom |
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Cancer Stem Cell News
Cell Therapy News
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ESC & iPSC News
Extracellular Matrix News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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