 | | Vol. 12.10 – 18 March, 2021 |
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| A periosteum mimicking bone aid with similar structure and function to natural periosteum was developed by electrospinning photocrosslinkable methacrylated gelatin, l‐arginine‐based unsaturated poly(ester amide), and methacrylated hydroxyapatite nanoparticles
[Small] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists combined analysis of pubertal mouse mammary glands, a 3D-printed engineered tissue model, and computational models of morphogenesis to investigate the origin and the dynamics of the global bias in epithelial orientation during pubertal mammary development.
[Current Biology] |
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| Researchers demonstrated that serum and glucocorticoid kinase-1 (SGK1) activation was necessary and sufficient for ATP generation during ECM detachment and anchorage-independent growth.
[Cell Reports] |
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| Scientists applied florescence-activated cell sorting, RNA sequencing and bioinformatic methods to investigate the common effects of cardiovascular disease risk factors in mouse cardiac endothelial cells.
[eLife] |
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| 37 cytokines/chemokines were identified at varying abundance, some of which involved in both chemotaxis and homeostasis of inflammatory cells and in positive remodeling of ECM, often damaged in tendinopathy and osteoarthritis.
[Stem Cells Translational Medicine] |
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| The authors showed that mesenchymal stem cells differentiated into cancer-associated fibroblasts, induced by the exosomes derived from gastric cancer cells.
[Cell Death & Disease] |
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| Scientists evaluated the occurrence of mutations affecting post-translational modification sites in matrisome genes across different tumor types, in light of their genomic and functional contexts and in comparison with the rest of the genome.
[Cancers] |
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| Researchers showed that FilGAP, a GTPase‐activating protein (GAP) for Rac, controlled front‐rear polarity and contributed to maintain effective tumor cell migration through the ECM.
[FASEB Journal] |
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| The authors found high expression of miR-151-3p in osteosarcoma tissues, and miR-151-3p derived from cancer associated fribroblast-extracellular vesicles promoted the process of epithelial–mesenchymal transition, migration, and invasion of MG63 cells.
[Cancer Gene Therapy] |
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| Investigators uncovered the hub long non-coding RNAs differentially expressed in osteoarthritis cartilage using an integrated analysis of the competing endogenous RNA network and co-expression network.
[Bone & Joint Research] |
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| Scientists present the recent developments in bifunctional biomaterials to achieve a new strategy for bone tumor therapy. The selected bifunctional materials include 3D-printed scaffolds, nano/microparticle-containing scaffolds, hydrogels, and bone-targeting nanomaterials.
[Bone Research] |
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| New tools known as tumor‐on‐a‐chip and metastasis‐on‐a‐chip have been recently proposed. These tools incorporate microfluidic systems and small culture chambers where tumor microenvironment can be faithfully modeled thanks to 3D bioprinting.
[Small] |
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| The authors analyze how the most prominent technologies and discoveries in the field converge towards the development of advanced constructs for skeletal regeneration.
[Acta Biomaterialia] |
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| Rubius Therapeutics, Inc. announced initial clinical, pharmacodynamic and tumor trafficking data from its ongoing Phase I/II clinical trial of RTX-240 in patients with advanced solid tumors.
[Rubius Therapeutics, Inc.] |
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| The South Korean government announced that it would spend 595 billion won ($525.6 million) by 2030 to support the country’s regenerative medicine sector.
[The Korea Herald] |
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| | STEMCELL Technologies, Inc. – Vancouver, British Columbia, Canada |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | Tulane School of Medicine – New Orleans, Louisiana, United States |
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| | University of Maryland School of Medicine – Baltimore, Maryland, United States |
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| | The University of Texas Southwestern Medical Center – Dallas, Texas, United States |
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Cell Therapy News
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Hepatic Cell News
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Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
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