 | | Vol. 12.19 – 20 May, 2021 |
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| Investigators demonstrated that eukaryotic cells sensed the physical properties of the extracellular matrix and activated a mitochondrial stress response that adaptively tunes mitochondrial function via solute carrier family 9 member A1-dependent ion exchange and heat shock factor 1-dependent transcription.
[Cell Metabolism] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists assessed the potential for electrospun decellularized skeletal muscle extracellular matrix (dECM) with tunable physicochemical properties to control mouse myoblast growth and myotube formation.
[Science Advances] |
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| Investigators reported that epithelial ductal elongation within human mammary organoid branches relied on the non-linear and plastic mechanical response of the surrounding collagen.
[Nature Communications] |
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| Scientists identified key regulatory pathways that distinguish the liver and lung tumor microenvironments in a preclinical mouse model of metastatic pancreatic ductal adenocarcinoma.
[Genome Biology] |
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| The authors used genetic fate mapping to establish that connective tissue cells form the post-metamorphic frog blastema, as in the case of axolotls.
[Developmental Cell] |
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| Researchers developed a spatial model of YAP/TAZ translocation to enable quantitative analysis of the relationships between substrate stiffness, substrate dimensionality, and cell shape.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Investigators focused on cancer-associated fibroblasts and their derived exosomes on the lymphoma microenvironment to uncover their clinical significance.
[Oncogene] |
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| Researchers analyzed the collagen and matrix metalloproteinase 1 (MMP1) expression in Neurofibromatosis 1 cutaneous neurofibroma and found excessive expression of collagen and reduced expression of MMP1.
[Cell Death & Disease] |
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| Investigators analyzed the associations between common clear cell renal cell carcinoma somatic mutations and immune cell infiltration patterns within the tumor immune microenvironment
[European Urology Focus] |
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| Researchers evaluated the intestinal segment-specific effects of diabetes and insulin replacement on ganglionic basement membrane thickness, matrix metalloproteinase 9, and tissue inhibitor expression.
[World Journal of Diabetes] |
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| Scientists review the compositional, microarchitectural, and mechanical hallmarks of cancer-associated ECM and highlight biomaterials and engineering approaches to recapitulate these properties for in vitro and in vivo studies.
[Current Opinion in Cell Biology] |
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| Investigators discuss advanced biomaterials where dynamic covalent chemistry is used to produce stable 3D cell culture models and high-resolution constructs for both in vitro and in vivo applications.
[Advanced Healthcare Materials] |
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| VIVEX Biologics, Inc. announced the launch of VIAGENEX™, a family of amniotic allografts processed to retain the inherent mechanical properties of amniotic tissue and rich supply of ECM, growth factors, and cytokines.
[VIVEX Biologics, Inc. (PR Newswire, LLC)] |
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| June 14 – 18, 2021
Virtual |
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| | Massachusetts General Hospital – Boston, Massachusetts, United States |
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| | University of Virginia – Charlottesville, Virginia, United States |
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| | University of Western Ontario – London, Ontario, United States |
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| | University of Nebraska Medical Center – Omaha, Nebraska. United States |
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| | Bristol Myers Squibb – Redwood City, California, United States |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
