 | | Vol. 12.30 – 12 August, 2021 |
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| A robotic manipulation platform that allowed wireless, localized, and programmable deformation of an engineered fibrous ECM was introduced.
[Advanced Materials] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists evaluated MUC5B variant rs35705950, telomere length, and serum levels of matrix metalloproteinase (MMP)-1, MMP-2, MMP-3, MMP-7, MMP-8, MMP-9, MMP-12, MMP-13, interleukin-6, surfactant protein-D, α-Klotho and resistin.
[European Respiratory Journal] |
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| Researchers demonstrated two engineering elements to improve human brain organoid culture, (1) a human brain ECM to provide brain-specific cues and (2) a microfluidic device with periodic flow to improve the survival and reduce the variability of organoids.
[Nature Communications] |
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| The authors focused on the collagen content in the cartilage cell microenvironment of healthy and osteoarthritic cartilage.
[Acta Biomaterialia] |
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| Patients’ gene expression profile from seven GEO databases was normalized after removing the batch effect. Tumor immune microenvironment (TIME) cell components were explored through Xcell tools and then hierarchically clustered to establish TIME classification.
[BMC Medicine] |
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| The expression of actin cytoskeleton and ECM proteins, myosin light chain phosphorylation in human trabecular meshwork cells were evaluated using real-time quantitative PCR, immunocytochemistry, and western blotting.
[Scientific Reports] |
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| Researchers presented an image analysis platform to analyze time-dependent dynamics observed in lung fibroblasts embedded in a 3D collagen matrix.
[Scientific Reports] |
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| Scientists found that the expression of matrix metallopeptidase 1 (MMP1) was up-regulated in cutaneous squamous cell carcinoma (CSCC) cells, and knockdown of MMP1 suppressed cell proliferation and invasion in CSCC.
[Cancer Biology & Therapy] |
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| Ultrastructural examination revealed a basement membrane-like ECM coat on the surface of blastuloids, but not moruloids or spheroids.
[Life Science Alliance] |
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| Hydrogel-based methods engineer physicochemical tissue properties to render intact organs optically transparent and size and shape adjustable while preserving biomolecules at their physiological locations.
[Cell] |
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| The authors cover and critically address the importance of ECM networks and their macromolecules in cancer.
[Trends in Molecular Medicine] |
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| The Office of Research recently awarded a total of $435,000 in three proof-of concept grant programs for faculty, while the Office of Public Scholarship and Engagement gave a total of $67,500 in seed and bridge grants to faculty for publicly engaged research projects.
[University of California, Davis] |
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| August 23 – September 2, 2021
Virtual |
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| | Gilead Sciences, Inc. – Foster City, California, United States |
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| | University of Michigan – Ann Arbor, Michigan, United States |
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| | Buck Institute for Research on Aging – Novato, California, United States |
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| | Oregon Health & Science University – Portland, Oregon, United States |
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| | University of Rochester – Rochester, New York, United States |
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