| Vol. 12.31 – 19 August, 2021 |
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| A microsphere embedded osteoinductive decellularized bone ECM/oleoyl chitosan based hydrogel construct was developed as a matrix allowing dual delivery of an anti-resorptive drug and BMP-2 for a focal tibial defect in a rabbit model. Amniotic membrane-derived stem cells cultivated on the hydrogel construct demonstrated excellent biocompatibility, cell viability, and active proliferation potential. [Journal of Materials Chemistry B] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators developed a network model of randomly oriented collagen and elastin fibers to represent pulmonary alveolar wall tissue. [Scientific Reports] |
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| Researchers presented an image analysis platform to analyze time-dependent dynamics observed in lung fibroblasts embedded in a 3D collagen matrix. [Scientific Reports] |
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| The authors synthesized and performed the physicochemical characterization and biocompatibility of a collagen-silica-based biocomposite for potential application in bone tissue engineering. [Journal of Biomedical Materials Research Part A] |
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| Scientists used atomic force microscopy to determine the impact of sequence heterogeneity on the local flexibility of collagen IV and of the fibril-forming collagen III. [Biophysical Journal] |
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| In this study, the esophageal extracellular matrix scaffold was successfully constructed by perfusion-decellularized technique through the vascular system for the first time. [Biomedical Materials] |
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| The inner surface of electrospun poly nanofibrous conduit was biofunctionalized with laminin containing brain derived neurotrophic factor (BDNF) and gold nanoparticles in chitosan nanoparticle. [BMC Neuroscience] |
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| Researchers explored the potential role of a highly selective caspase-1 inhibitor, VX-765, on extracellular matrix accumulation and inflammation in diabetic nephropathy and the underlying mechanisms. [Journal of Pharmacy and Pharmacology] |
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| Lysine-specific demethylase 1 significantly impacted on the progression of TGF-β1-mediated epithelial-mesenchymal transition and ECM deposition in HK-2 cells, and it may represent novel target for the prevention strategies of renal fibrosis. [Human & Experimental Toxicology] |
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| The authors bring together emerging understanding of basement membrane defects within the heart including in common cardiovascular pathologies such as contractile dysfunction and highlight some key questions that are now ready to be addressed. [Bioscience Reports] |
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| Orizuru Therapeutics, Inc. (OZTx) announced the launch of its operations. OZTx is a research and development-driven company focusing on the development of iPSC-based regenerative medicine and the application of iPSC technology. [Orizuru Therapeutics, Inc.] |
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| September 12 – 15, 2021 St. Louis, Missouri, United States |
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| Revel Pharmaceuticals – San Francisco, California, United States |
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| Michigan State University – East Lansing, Michigan, United States |
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| Gilead Sciences, Inc. – Foster City, California, United States |
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| Danaher – Toronto, Ontario, Canada |
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| Buck Institute for Research on Aging – Novato, California, United States |
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