| Vol. 12.33 – 2 September, 2021 |
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| Longitudinal analyses of the tissue proteome through the course of naturally developing disease in recessive dystrophic epidermolysis bullosa mice revealed that increased pro-inflammatory immunity associates with fibrosis evolution. [EMBO Molecular Medicine] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| A rabbit alveolar process cleft model was established by removing the bone tissue from the left maxillary bone. 48 young Japanese white rabbits were divided into normal, control, material and mesenchymal stem cell groups. [Stem Cell Reviews and Reports] |
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| Researchers established through a clinical cohort and preclinical models that the interaction of vitronectin and its ligands, such as αv integrins, were related to the stiffness of the ECM in high-risk neuroblastoma. [International Journal of Pharmaceutics] |
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| Scientists investigated whether baseline serum levels of the pro-fibrotic matrix metalloproteinase 2 (MMP2), MMP7 and their inhibitor, tissue inhibitor of metalloproteinase 1, were associated with glomerular filtration rate decline in a general nondiabetic population. [Nephrology Dialysis Transplantation] |
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| The authors compared C-reactive protein (CRP) and matrix metalloproteinase-generated neoepitope of CRP as biomarkers of inflammation and radiographic severity in patients with knee osteoarthritis. [Arthritis Research & Therapy] |
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| Researchers investigated arthritis development in male DBA/1 mice which were injected with bovine collagen II and human fibrinogen on days 0 and 21, leading to stable and reproducible disease induction in 100% of immunized mice. [Scientific Reports] |
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| Investigators sampled four different collagen samples using standard mass spectrometry (MS) and MS/MS techniques. [PLOS One] |
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| 3D Organoids were grown in an extracellular matrix and characterized by qPCR. Organoids were also seeded on permeable filter supports in order to generate 2D epithelial monolayers. [PLoS One] |
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| Investigators clarified the relationship between Endo180 reduction and the decrease in type I collagen fibers observed in photoaged dermis. [Photodermatology, Photoimmunology & Photomedicine] |
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| Scientists discuss engineered living materials that incorporate microorganisms as the living, bioactive component. They highlight biomedical applications of such engineered living materials, including biosensing, wound healing, stem-cell-based tissue engineering and drug delivery, and provide an outlook to the challenges and future applications of engineered living materials. [Nature Reviews Materials] |
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| The authors survey the complexity involved in spinal ECM modifications, discuss new ECM-based combinatorial strategies, and explore biomaterials evaluated in clinical trials which hope to introduce new treatments that enhance recovery after spinal cord injury. [Antioxidants & Redox Signaling] |
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| A University of Miami Miller School of Medicine research team has launched a Phase III multicenter clinical trial to evaluate the effectiveness of mesenchymal stem cells in treating COVID-19 patients with acute respiratory distress syndrome. [University of Miami] |
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| Orthofix Medical, Inc. announced the launch and first patient implants with the fiberFUSE™ Strip, an advanced demineralized fiber bone-graft solution containing cancellous bone. The fiberFUSE Strip is formulated as a convenient preformed bone-graft strip to enable optimized application for posterior cervical, posterior lumbar and degenerative spinal procedures. [Orthofix Medical, Inc.] |
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| October 7 – 11, 2021 Virtual |
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| St. Jude Children’s Research Hospital – Memphis, Tennessee, United States |
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| University College London – London, England, United Kingdom |
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| Sidney Kimmel Cancer Center at Jefferson Health – Philadelphia, Pennsylvania, United States |
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| Duke University – Durham, North Carolina, United States |
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| Michigan State University – East Lansing, Michigan, United States |
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