 | | Vol. 12.35 – 16 September, 2021 |
| |
|
|
| Experimental in vitro models that capture pathophysiological characteristics of human tumours are essential for basic and translational cancer biology. Researchers described a fully synthetic hydrogel extracellular matrix designed to elicit key phenotypic traits of the pancreatic environment in culture.
[Nature Materials] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Using cellular cryo-electron tomography, investigators resolved the ultrastructure of the tropomyosin/actin copolymers and showed that they specifically anchored to nascent adhesions and were essential for focal adhesion assembly.
[Nature Materials] |
|
|
|
| Scientists developed hydrogels that enabled mouse embryonic stem cells (mESCs) to maintain stemness in vitro in the absence of both leukemia inhibitory factor and mouse embryonic fibroblasts, two critical factors in the standard protocol for mESC maintenance.
[ACS Nano] |
|
|
|
| Researchers demonstrated a chemical approach, termed “switchable” immune modulator, to limit the systemic exposure and therefore ameliorate their toxicities.
[Science Advances] |
|
|
|
| Investigators indicated that interleukin-11 signaling in endothelial cells antagonized profibrotic transforming growth factor–β signaling and endothelial-to-mesenchymal transition, limiting scarring and promoting cardiomyocyte repopulation, after injury.
[Science Advances] |
|
|
|
| Using multiple screening assays upstream and downstream of miR-29a signaling, the authors located the secreted protein and adipogenic inhibitor SPARC to an fibroblast growth factor-2 (FGF-2) signaling pathway that was conserved between skeletal muscle cells from mice and humans and that was activated in skeletal muscle of aged mice and humans.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
| Scientists reported that active integrins accumulated at the tip of myosin-X (MYO10)-positive filopodia, while inactive integrins were uniformly distributed, and identified talin and MYO10 as the principal integrin activators in filopodia.
[Cell Reports] |
|
|
|
| Investigators proposed a methodology to fabricate hierarchical multiscale scaffolds with controlled hydrophilic and hydrophobic properties by employing capillary force lithography in combination with plasma modification.
[NPJ Regenerative Medicine] |
|
|
|
| A set of formulations consisting of photo-polymerizable gel; photo-polymerizable hyaluronic acid, and allogenic decellularized cartilage matrix, was synthesized and characterized.
[NPJ Regenerative Medicine] |
|
|
|
| Researchers investigated the possible effect of bioactive glass (BG) on pyroptosis in wound healing both in vivo and in vitro and showed that BG could accelerate wound closure, granulation formation, collagen deposition, and angiogenesis.
[Laboratory Investigation] |
|
|
|
| The authors demonstrated that TC10, a member of a Cdc42 subfamily of p21 small GTPases, regulated the membrane type 1 matrix metalloproteinase-driven extracellular matrix degradation at invadopodia.
[Communications Biology] |
|
|
|
| Performing in situ hybridization and immunofluorescence analysis, investigators found that mouse Hmcn1 and Hmcn2 showed a complementary distribution throughout different tissues and developmental stages.
[Scientific Reports] |
|
|
|
| Scientists constructed an artificial vascular tissue constructed by human adipose tissue-derived stromal cells and umbilical vein-derived endothelial cells by a modified technique with cryopreservation.
[Scientific Reports] |
|
|
|
|
| Investigators discuss biomaterial-based non-antibiotic antibacterial therapies for the treatment of community-acquired and hospital-acquired infectious diseases, with a focus on in vivo results.
[Nature Reviews Materials] |
|
|
|
| The authors discuss some of the leading burn wound pathogens and outline how they regulate biofilm formation in the burn wound microenvironment, the new and emerging models that are available to study burn wound biofilm formation in vivo.
[NPJ Biofilms and Microbiomes] |
|
|
|
|
| Fuse Medical, Inc. announced the official launch of the FuseChoice™ Dermal Matrix line. FuseChoice™ Derm has been developed by using a proprietary process to preserve the inherent properties of key extracellular matrix molecules, such as collagen and elastin, while maintaining excellent tensile strength to maintain its framework with intact vascular channels.
[Fuse Medical, Inc.] |
|
|
|
|
| November 29 – December 1, 2021
Barcelona, Spain |
|
|
|
|
|
| | Houston Methodist Research Institute – Houston, Texas, United States |
|
|
|
| | University of Southern California – Los Angeles, California, United States |
|
|
|
| | University of Glasgow – Glasgow, Scotland, United Kingdom |
|
|
|
| | Duke University – Durham, North Carolina, United States |
|
|
|
| | Epitopea – Cambridge, England, United Kingdom |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
