Extracellular Matrix News Volume 3.01 | Jan 12 2012

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    Extracellular Matrix News 3.01, January 12, 2012

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         In this issue: PublicationsIndustry News | Policy News | Events | Jobs
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    TOP STORY

    recipientid">Extracellular Matrix in Airway Smooth Muscle Is Associated with Dynamics of Airway Function in Asthma
    First, researchers investigated the difference in extracellular matrix (ECM) expression in airway smooth muscle between asthma and controls. Second, they examined whether ECM expression is associated with bronchoconstriction and bronchodilation in vivo. [Allergy] recipientid">Abstract

    EmailAddress&u=http://www.stemcell.com/en/Forms/Multimedia/Archived-Webinar-Affordable-Defined-hPSC-Culture.aspx?id=Affordable, Defined hPSC Culture? StemAdhere%e2%84%a2 %e2%80%9cSticks it%e2%80%9d to Other Matrices%26utm_source=ecm%26utm_medium=banner%26utm_campaign=webinar_stemadhere_video_645x110&t=(A)ECM3.01i">Webinar: Affordable, Defined hPSC Culture?  Watch the video now.

    PUBLICATIONS (recipientid">Ranked by Impact Factor of the Journal)

    recipientid">Integrins Regulate Repulsion-Mediated Dendritic Patterning of Drosophila Sensory Neurons by Restricting Dendrites in a 2D Space
    Removing neuronal integrins or blocking epidermal laminin production causes dendrites to grow into the epidermis, suggesting that integrin-laminin interaction attaches dendrites to the extracellular matrix. [Neuron] recipientid">Abstract

    recipientid">Newly Visualized Fibrillar Collagen Scaffolds Dictate Entamoeba histolytica Invasion Route in the Human Colon
    In this study, investigators determined the impact of the collagen fibers architecture on the invasive process of the enteric parasite Entamoeba histolytica. [Cell Microbiol] recipientid">Abstract

    recipientid">Distinct Recycling of Active and Inactive ß1 Integrins
    Data provide new insights into the endocytic traffic of integrins and imply the possibility of a previously unappreciated cross-talk between pathways regulating integrin activity and traffic. [Traffic] recipientid">Abstract

    recipientid">Micro- and Macrorheology of Jellyfish Extracellular Matrix
    Investigators found that the extracellular matrix behaved as a viscoelastic gel at the macroscopic scale and as a much softer and heterogeneous viscoelastic structure at the microscopic scale. [Biophys J] recipientid">Abstract

    recipientid">Altered Synaptic Marker Abundance in the Hippocampal Stratum Oriens of Ts65Dn Mice Is Associated with Exuberant Expression of Versican
    The purpose of this study was to identify changes in synaptic structure in the hippocampus in a model of Down syndrome, the Ts65Dn mouse, and to determine the relationship to proteoglycan abundance and/or cleavage and cognitive disability. [ASN Neuro] recipientid">Abstract

    recipientid">Maladaptive Matrix Remodeling and Regional Biomechanical Dysfunction in a Mouse Model of Aortic Valve Disease
    The objective of this study was to examine extracellular matrix remodeling and biomechanical properties in regional aortic valve tissue and determine the impact of early aortic valve malformation on late aortic valve disease in the elastin insufficient mouse model. [Matrix Biol] recipientid">Abstract

    recipientid">Mechanical Properties of Tyramine Substituted-Hyaluronan Enriched Fascia Extracellular Matrix
    The objective of this study was to determine the extent to which tyramine substituted-hyaluronan treatment was associated with mechanical property changes of fascia after implantation in the rat model. [J Biomed Mater Res A] recipientid">Abstract

    recipientid">Collagen-Silica Xerogel Nanohybrid Membrane for Guided Bone Regeneration
    Findings suggest that the collagen-silica xerogel hybrid can be used as a guided bone regeneration membrane. [J Biomed Mater Res A] recipientid">Abstract

    recipientid">Heparan Sulfate Niche for Cell Proliferation in the Adult Brain
    To determine to which extent cell proliferation is associated with N-sulfated heparan sulfates (N-sulfated HS), investigators mapped N-sulfated HS and proliferating cells by immunohistochemistry throughout the adult mouse brain. [Neurosci Lett] recipientid">Abstract

    EmailAddress&u=http://www.stemcell.com/EN/Technical-Resources/3a131/Optimization-of-ALDEFLUOR-Protocol.aspx?utm_source=ecm%26utm_medium=banner%26utm_campaign=OptProtVideo&t=(A)ECM3.01ii">Watch the Video: Optimize Your ALDHbr Cell Detection with Tissue-Specific ALDEFLUORâ„¢ Protocols

    INDUSTRY NEWS

    recipientid">Biomerix Receives CE Mark Approval For ASSURE Soft Tissue Repair Mesh
    Biomerix Corporation announced that it has received CE Mark approval for its ASSURE soft tissue repair mesh, a novel composite mesh intended for the reconstruction of hernias and soft tissue deficiencies and for the temporary bridging of fascial defects. [Biomerix Corporation] recipientid">Press Release

    recipientid">Rice's Grande-Allen wins AHA Established Investigator Award
    Rice University's Jane Grande-Allen, one of the world's foremost experts on the biomechanics of heart-valve tissue, has won an Established Investigator Award from the American Heart Association. Grande-Allen's specialty is studying the unique biological and material properties of valves so doctors can better understand and treat valve disease. [Rice University] recipientid">Press Release

    POLICY NEWS

    recipientid">National Institutes of Health (United States)

    recipientid">Food and Drug Administration (United States)

    recipientid">Center for Biologics Evaluation and Research (United States)
     
    recipientid">European Medicines Agency (European Union)

    recipientid">Medicines and Healthcare Products Regulatory Agency (United Kingdom)

    Therapeutic Goods Administration (Australia)

    EVENTS

    NEW recipientid">Keystone Symposia on Molecular and Cellular Biology: Structural Biology of Cellular Processes
    January 22-27, 2012
    Keystone, United States

    NEW Molecular Medicine Tri-Conference 2012
    February 19-23, 2012
    San Francisco, United States

    Visit recipientid">our events page to see a complete list of events in the extracellular matrix community.

    JOB OPPORTUNITIES

    recipientid">Research and Development Technologist, hPSC Media (STEMCELL Technologies)

    recipientid">Scientist - Pluripotent Stem Cells (STEMCELL Technologies)

    recipientid">Research Technologist, Manufacturing Sciences (STEMCELL Technologies)

    recipientid">Business Analyst - Product Management (STEMSOFT Software)

    recipientid">Postdoctoral Positions - Tissue-Engineering (Sabanci University)

    recipientid">Postdoctoral Position - Molecular Cell Biology (Weizmann Institute of Science)

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