The Host Response to Endotoxin Contaminated Dermal Matrix Researchers examined the in vitro and in vivo effects of endotoxin contamination within an extracellular matrix scaffold derived from porcine dermis upon the host immune response and the downstream ability of the scaffold material to promote constructive tissue remodeling. [Tissue Eng Part A] Abstract
SPARC/SFN Interaction, Suppresses Type I Collagen in Dermal Fibroblasts Scientists determined that stratifin (SFN) and SPARC form a complex thereby controlling the type I collagen synthesis and expression in fibroblasts. The levels of these proteins in fibrotic tissues were also evaluated and a differential expression of these proteins between normal and fibrotic tissue confirmed their potential role in development of fibrotic condition. [J Cell Biochem] Abstract
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