Cancer-Associated Fibroblasts Regulate the Plasticity of Lung Cancer Stemness via Paracrine Signaling Investigators established a sustainable primary culture of Oct3/4+/Nanog+ lung cancer stem cells fed with CD90+ cancer-associated fibroblasts to further advance the knowledge of preserving stem cells in the tumor microenvironment. [Nat Commun] Abstract Transplantation of Bone Marrow Mesenchymal Stem Cells on Collagen Scaffolds for the Functional Regeneration of Injured Rat Uterus Researchers investigated the effect of collagen/bone marrow-derived mesenchymal stem cells constructs in the healing of severe uterine injury in rats (partial full thickness uterine excision). [Biomaterials] Abstract Cryopreserved Dentin Matrix as a Scaffold Material for Dentin-Pulp Tissue Regeneration Scientists hypothesized that the cryopreservation could effectively maintain the survival and viability of dentinogenesis-related proteins of treated dentin matrix and the cryopreserved dentin matrix would provide the suitable biological scaffold and inductive microenvironment for the regeneration of dentin-pulp like tissue. [Biomaterials] Abstract Three-Dimensional Hydrogel Scaffolds Facilitate In-Vitro Self-Renewal of Human Skin-Derived Precursors Taking the physiological micro-environment of human skin-derived precursors (hKSPs) into consideration, scientists sought to establish a hydrogel scaffold-based three-dimensional culture system for hSKPs. [Acta Biomater] Abstract A Novel Peptide-Based Platform for the Dual Presentation of Biologically-Active Peptide Motifs on Biomaterials Investigators introduce a novel peptide-based divalent platform with the capacity to simultaneously present distinct bioactive peptide motifs in a chemically controlled fashion. [ACS Appl Mater Interfaces] Abstract Comparative Proteomic Analysis of Human Lung Telocytes with Fibroblasts Investigators examined the molecular aspects of lung telocytes (TCs) by comparison with fibroblasts. TC proteins with known identities are localized in the cytoskeleton and plasma membrane, while fibroblast up-regulated proteins are in the cytoskeleton and destined to extracellular matrix. [J Cell Mol Med] Full Article Fibroblast-Like Cells Differentiated from Adipose-Derived Mesenchymal Stem Cells for Vocal Fold Wound Healing Scientists implanted fibroblast-like cells differentiated from adipose-derived mesenchymal stem cells in a canine acute vocal fold wound model. Investigators then sought to characterize changes in the extracellular matrix proteins of vocal fold lamina propria. [PLoS One] Full Article Adapted Chondrogenic Differentiation of Human Mesenchymal Stem Cells via Controlled Release of TGF-β1 from Poly(Ethylene Oxide)-Terephtalate / Poly(Butylene Terepthalate) Multiblock Scaffolds Investigators evaluated the ability of porous scaffolds composed of poly(ethylene oxide)-terephtalate and poly(butylene terepthalate) to release bioactive TGF-β1 for chondrogenesis of human bone marrow mesenchymal stem cells in a pellet culture model. [J Biomed Mater Res A] Abstract |