| Vol. 12.38 – 1 October, 2020 |
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| Knockdown of S100A10 in breast cancer cells suppressed their invasion abilities and overexpression of S100A10 in breast cancer patient‐derived tumor xenograft cells and 3D organoid formation capacities enhanced them in vitro. [Cancer Science] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists used intravenously delivered iodine nanoparticles with human TNBC tumors growing in the brains of athymic nude mice. [Scientific Reports] |
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| By qualitatively and quantitatively monitoring the real-time movements of live cells, researchers provided the first evidence that apple polyphenol extract inhibited the migration of MDA-MB-231 and MDA-MB-468 TNBC cells and downregulated metalloproteinase-2 and metalloproteinase-9. [Scientific Reports] |
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| The authors described an eco-friendly approach for in situ immobilization of Au nanoparticles on the surface of Fe3O4 nanoparticles, with help of Agar and ultrasound irradiations, without using any toxic reducing and capping agents. [International Journal of Biological Macromolecules] |
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| Scientists examined whether rMV-SLAMblind was effective for treating TNBC. Results suggested rMV-SLAMblind to be a promising candidate as a therapeutic agent for treating metastatic and/or TNBC. [Molecular Therapy-Oncolytics] |
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| Researchers found that miR-512-3p acted as a cell-type-specific tumor suppressor, through targeting HER2, HER3, PIK3R2, and AKT1 transcripts. [Breast Cancer Research and Treatment] |
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| The authors investigated the effects of sodium propionate on the proliferation, apoptosis, autophagy, and antioxidant production of breast cancer cells. [Acta Pharmacologica Sinica] |
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| LINC00665 expression levels were determined using quantitative polymerase chain reaction analysis with breast cancer tissues and cell lines. [Cellular & Molecular Biology Letters] |
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| Scientists investigated whether Newcastle disease virus (NDV)‐D90, a novel strain isolated from natural sources in China, promoted apoptosis by modulating the expression of ERα or the G protein estrogen receptor in breast cancer cells exposed to 17β‐estradiol. [Journal of Cellular Biochemistry] |
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| As both prostate and breast cancers often share a reliance on nuclear hormone signaling, there is increasing appreciation of the overlap between activated cellular pathways in these cancers in response to androgen signaling. [npj Breast Cancer] |
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| Olema Oncology announced the closing of a $85 million Series C financing. Olema used the financing proceeds to advance the clinical development of OP-1250, its lead product candidate in breast cancer, and expand ongoing research and development activities. [Olema Oncology] |
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| Researchers affiliated with the Cancer Center at Illinois discovered a novel small molecule compound that is now the subject of a new global licensing agreement between the pharmaceutical company Bayer AG and the cancer drug development company, Systems Oncology LLC. [Cancer Center at Illinois] |
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| October 13 – October 14 Virtual |
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| Princess Margaret Cancer Center – Toronto, Ontario, Canada |
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| University of Miami – Miami, Flordia, United States |
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| Cedars-Sinai Medical Center – Los Angeles, California, United States |
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| German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| Karlsruhe Institute of Technology – Karlsruhe, Germany |
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