 | | Vol. 12.30 – 4 August, 2020 |
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| Investigators identified a transcription factor-independent role of CLOCK, a core component of the molecular circadian clock machinery, in counteracting human MSC decay.
[Cell Research] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers showed MIR22HG, which has been demonstrated to be involved in the progression of several cancer types, played an important role in regulating bone marrow MSC osteogenesis.
[Cell Death & Disease] |
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| Investigators demonstrated that Celastrol promotes osteoblast differentiation and prevents adipocyte differentiation in bone marrow mesenchymal stem cells in vitro.
[Aging] |
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| Tissue spheroids, made of human adipose-derived stem cells, were differentiated in three dimensions into chondrogenic and osteogenic spheroids, which were confirmed by immunostaining and histology qualitatively, and biochemistry assays and gene expression, quantitatively.
[Scientific Reports] |
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| Researchers investigated up- and down-regulated genes in response to (thermo)radiotherapy in HSP70 proficient and deficient canine osteosarcoma cell line, and functional role of HSP70 in the mechanism of thermoradiosensitization.
[Scientific Reports] |
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| Adipose tissue MSCs were able to delay the onset of collagen-induced arthritis, suppress the ongoing clinical and histopathological signs, decrease serum levels of TNF-α and anti-collagen type II, and downregulate the autoreactive T cells as etanercept.
[Immunologic Research] |
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| Iron sucrose-labeled adipose-derived MSCs were tracked using T2-and T2∗-weighted sequences by 1.5 and 3 T MRI in an in vitro model.
[Heliyon] |
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| Exosomes were isolated from control and IFN-γ-primed MSCs and were verified by transmission electron microscope and immunofluorescence staining.
[Cell Death & Disease] |
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| Scientists investigated whether a bioengineered scaffold device containing hypoxia‐preconditioned, allogeneic human MSCs combined with the beta‐adrenergic antagonist timolol could improve impaired wound healing in diabetic mice.
[Stem Cells Translational Medicine] |
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| Researchers investigated the effect of conditioned medium derived from human embryonic MSCs on experimental ischemic stroke.
[Journal of Cellular Physiology] |
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| Investigators provide a concise overview of the contextual contribution of fibroblastic mesenchymal cells in physiology and disease and bring into focus emerging evidence for both their heterogeneity at the single-cell level and their tissue-specific, spatiotemporal functional diversity.
[Nature Immunology] |
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| Calidi Biotherapeutics, Inc. announced that the Investigational New Drug application submitted by its partner, Personalized Stem Cells, Inc., has received FDA approval for the treatment of COVID-19 and pneumonia patients using stem cell therapy.
[Calidi Biotherapeutics] |
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| Research advocates were eager to learn who Health and Human Services Secretary Alex Azar would appoint to the board and to see its ideological makeup. On July 31st they got their first look as it gathered online for a one-time meeting run by the National Institutes of Health.
[ScienceInsider] |
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| October 4 – October 7
Virtual |
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| | Nanyang Technological University – Singapore, Singapore |
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| | Nanyang Technological University – Singapore, Singapore |
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| | KU Leuven – Leuven, Belgium |
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| | University of Connecticut Health – Farmington, Connecticut, United States |
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| | Helmholtz Zentrum München – Neuherberg, Germany |
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