| Vol. 13.34 – 31 August, 2021 |
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| Researchers developed an in situ representation of the cardiac extracellular matrix (ECM) that was useful for assessment of repopulation dynamics and to study the effect of local ECM composition on phenotype preservation of reseeded mesenchymal progenitor cells. [Stem Cells] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists compared stem cell properties of dental pulp-derived human MSCs at passages 5, 10 and 20 under serum and serum-free culture conditions. Cell morphology, proliferation capacity, chromosomal stability, surface phenotypic profiles, differentiation and immunoregulation ability were evaluated. [Stem Cell Research & Therapy] |
| | Investigators showed that mesenchymal stromal cells from selected donors and NKTert, a stromal cell line, which is commonly used for co-culture studies with primary leukemia cells, extensively phagocytosed apoptotic cells. [iScience] |
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| Exosomes from the procured human bone marrow-MSCs were extracted and identified. Cancer stem cells from hepatocellular carcinoma cell lines were collected. [Human Cell] |
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| Using a gradient change of detergents and continuous agitation, scientists developed a unique technique to generate completely cell-free amnion and chorion scaffolds. The absence of cellular components and integrity of biological and mechanical cues within decellularized human amnion and chorion were evaluated and compared with fresh membranes. [Tissue and Cell] |
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| The authors investigated the functional mechanism of exosomal microRNA‐96 derived from bone marrow MSCs in myocardial toxicity induced by doxorubicin. [Journal of the American Heart Association] |
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| Real-time qualitative PCR and Western blot analysis were conducted to determine expression of HGF, PTEN, and osteoblast differentiation-related genes in ovariectomy-induced osteoporosis mice and the isolated bone marrow MSCs. [Therapeutic Advances in Chronic Disease] |
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| Researchers investigated arthritis development in male DBA/1 mice which were injected with bovine collagen II and human fibrinogen on days 0 and 21, leading to stable and reproducible disease induction in 100% of immunized mice. [Scientific Reports] |
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| Scientists evaluated the clinical outcomes of the frozen autograft reconstruction focusing on skeletally mature adolescents and young adults that was 15 to 39 years of age. [Scientific Reports] |
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| The authors successfully established laparoscopic liver ischemia-reperfusion with partial hepatectomy in miniature pigs and injected saline, DMEM, adipose-derived stem cell (ADSC)-secretome, and ADSCs directly into the liver parenchyma immediately afterwards. [Stem Cells International] |
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| One therapeutic approach showing a ray of hope to combat COVID-19 infection is MSC therapy. Mesenchymal cells have immunomodulatory, anti-inflammatory as well as regenerative properties and various preliminary studies have shown that MSCs can reverse the lung damage and overcome the cytokine storm incited by COVID-19 infection. [Life Sciences] |
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| | BioRestorative Therapies, Inc. announced that the Japanese Patent Office has issued the company a patent related to its metabolic ThermoStem® Program. Claims granted under the new patent cover methodologies related to brown adipocytes from human brown adipose-derived stem cells. [BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)] |
| | Orthofix Medical, Inc. announced the launch and first patient implants with the fiberFUSE™ Strip, an advanced demineralized fiber bone-graft solution containing cancellous bone. The fiberFUSE Strip is formulated as a convenient preformed bone-graft strip to enable optimized application for posterior cervical, posterior lumbar and degenerative spinal procedures. [Orthofix Medical, Inc.] |
| | A University of Miami Miller School of Medicine research team has launched a Phase III multicenter clinical trial to evaluate the effectiveness of mesenchymal stem cells in treating COVID-19 patients with acute respiratory distress syndrome. [University of Miami] |
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| October 13 – 14, 2021 Virtual |
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| Banner MD Anderson Cancer Center – Gilbert, Arizona, United States |
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| Duke University – Durham, North Carolina, United States |
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| Baylor College of Medicine – Houston, Texas, United States |
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| Michigan State University – East Lansing, Michigan, United States |
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| Danaher – Toronto, Ontario, Canada |
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