 | | Vol. 23.38 – 28 September, 2021 |
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| Scientists examined the effects of plasma from myeloma patients at diagnosis and in complete remission and from healthy donors on the osteoblastic differentiation of healthy donor-derived adipose-dervied MSCs.
[Leukemia] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| The authors investigated the effect of retinoic acid and taurine in differentiation of the human bone marrow stem cell into cone photoreceptors cells and retinal ganglion cells.
[Journal of Cellular Biochemistry] |
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| The osteogenic role of prepared complex under in vivo was studied by an in-house zebrafish scale model followed by osteoblast differentiation markers expression profiling and Ca:P level measurement by ICP-MS.
[Chemico-Biological interactions] |
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| MSC aggregation into spheroids was optimized in vitro based on cellular viability, spheroid size, and trophic factor secretion. The regenerative potential of the optimized MSC spheroid therapy was then investigated in a murine model of volumetric muscle loss injury.
[Tissue Engineering and Regenerative Medicine] |
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| The authors found that the period in which avascular mesenchymal condensation became a vascularized bone structure corresponds to embryonic day 14.5 to embyronic day 16.5 in the hard palate.
[Journal of Anatomy] |
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| A Phase Ib study was conducted to evaluate the safety and immunoregulatory mechanism of action of MSCs using a novel ex vivo product to preserve cell activity in patients with severe acute kidney injury.
[Stem Cells Translational Medicine] |
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| The difference in the effect of killer immunoglobulin-like receptor–ligand mismatch (KIR)–ligand mismatch was retrospectively assessed between patients who received cord blood transplantation for acute leukemia, myelodysplastic syndrome, or chronic myeloid leukemia, as well as GVHD prophylaxis comprising tacrolimus plus methotrexate or mycophenolate mofetil.
[Bone Marrow Transplantation] |
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| Critical limb ischemia in type 2 diabetes mouse model was used to explore the impact of diabetic limb ischemia on the survival of bone marrow mesenchymal stromal cells.
[Journal of the American Heart Association] |
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| To determine how a prolonged treatment could impair their functional characteristics, scientists exposed human MSCs to increasing morphine concentrations respectively for nine and eighteen days, evaluating in particular the fibrogenic potential exerted by the long-term exposition.
[Scientific Reports] |
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| Murine adipose-derived MSC line m17.ASC was cultured in agarose-based microwell plates to obtain size-controlled m17.ASC spheroids of an average diameter and cell number of approximately 170 μm and 1100 cells/spheroid, respectively.
[Biotechnology Journal] |
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| Investigators examined the effects of stem cells derived from amniotic fluid and MSCs on the prevention of intestinal injury during experimental necrotizing enterocolitis.
[Pediatric Research] |
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| The possible roles of human umbilical MSCs and adipose mesenchymal stem cells in neurogenesis and synaptic function were investigated using a β-amyloid 1-42-induced Alzheimer’s disease rat model.
[Heliyon] |
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| Investigators recapitulate the molecular basis of bone marrow (BM)MSC-assisted biological processes and summarizes the possible mechanisms related to the interaction between BMMSCs and microglia.
[Journal of Inflammation Research] |
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| The authors summarize current knowledge on how stem cell-derived nanovesicles regulate immunity, fibroblast activity, angiogenesis, and scar formation in the wound healing process.
[Stem Cells International] |
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| Bone Therapeutics and Implant Therapeutics announced the signing of a research evaluation agreement. The agreement will enable Bone Therapeutics to access, evaluate and materially transfer Implant Therapeutics’ iPSC lines, media, differentiation protocols and expertise.
[Bone Therapeutics] |
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| A researcher at the University of Kansas has earned a five-year, $1.25 million Maximizing Investigators’ Research Award from the National Institutes of Health to study how estrogen interacts with the body at the level of the cell microenvironment.
[Universityof Kansas (News-Medical.Net)] |
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| October 19, 2021
London, England, United Kingdom |
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| | University of Copenhagen – Copenhagen, Denmark |
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| | NHS Blood and Transplant – Oxford, England, United Kingdom |
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| | King Abdullah University of Science and Technology – Thuwal, Saudi Arabia |
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| | Broad Institute – Cambridge, Massachusetts, United States |
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| | University of Southern California – Los Angeles, California, United States |
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