 | | Vol. 23.40 – 12 October, 2021 |
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| A facile 3D-bioassembly platform was introduced to primarily study fusion of cartilage–cartilage interfaces using spheroids formed from human MSCs and articular chondrocytes.
[Advanced Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| The effect of MSCs on proliferation of anti-CD3/CD28-stimulated T CD4+ cells and generation of regulatory T cels with or without pre-treatment with mitomycin C, IFN-γ and IL-1β was evaluated by flow cytometry.
[Stem Cell Research & Therapy] |
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| Investigators analyzed RNA-sequence data to reveal expression profiles of circular RNAs during osteogenesis of human umbilical cord MSCs, then elucidated the underlying mechanisms of action.
[Scientific Reports] |
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| Peripheral blood and endometrial (e)MSC specimens were collected from suspected women of endometriosis before laparoscopy. Total RNA was isolated from plasma and cultured eMSCs to synthesize complementary DNA.
[Biomed Research International] |
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| Scientists tested whether human induced-pluripotent stem-cell-derived MSCs would offer an additional benefit to the rodent with acute kidney injury associated sepsis syndrome undergoing ciprofloxacin therapy.
[Stem Cell Research & Therapy] |
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| Researchers conducted a safety and efficacy study that included ten patients with a median age of 50 years with COVID-19-induced acute respiratory distress syndrome (ARDS).
[Journal of Cellular and Molecular Medicine] |
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| The authors showed that isolated CD73-EGFP+ MSCs displayed more pronounced stemness and stronger in vitro differentiation capacity into the osteogenic lineage compared to CD73-EGFP−MSCs.
[Bone Reports] |
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| Explanted aortic valve constructs from female Hartley guinea pigs were procured and decellularized, followed by recellularization with autologous Sprague-Dawley rat mesenchymal stem cells.
[European Journal of Cardio-Thoracic Surgery] |
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| Scientists treated ulcerative colitis animals with MSC preconditioned with or without H19 and compared the therapeutic effect of MSC and MSC-H19.
[Disease Markers] |
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| Investigators discuss potential mechanisms of action for the therapeutic effects of MSC transplantation, experimental models that dissect tissue modulating function of MSCs, and approaches for identifying MSC effects in vivo by integrating biomarkers of disease and MSC activity.
[Cell Stem Cell] |
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| Tissue-specific MSC identities, fates, and function(s) are being resolved through fate mapping coupled with single cell “omics,” providing unparalleled insights into the secret lives of tissue-resident MSCs.
[Cell Stem Cell] |
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| The authors discuss adiposopathy with a focus on adiponiche dysfunction, and underline the mechanisms that control adipose tissue expansion and energy balance.
[Trends in Endocrinology and Metabolism] |
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| Cynata Therapeutics Limited has entered into a new strategic partnership with Fujifilm Corporation which includes agreed core terms for Fujifilm to provide clinical & commercial manufacturing services for, as well as supply of, the vompany’s Cymerus™ therapeutic MSC products.
[Kalkin Media] |
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| Whitehead Institute Member Pulin Li has received a New Innovator Award from the National Institutes of Health (NIH). Li’s New Innovator Award will fund her investigations of how the different cell types in the body interact to form organs.
[Whitehead Institute] |
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| November 1 – 3, 2021
Virtual |
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| | University of Connecticut – Farmington, Connecticut, United States |
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| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
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| | University of Copenhagen – Copenhagen, Denmark |
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| | King Abdullah University of Science and Technology – Thuwal, Saudi Arabia |
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| | Broad Institute – Cambridge, Massachusetts, United States |
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