 | | Vol. 13,49 – 14 December, 2021 |
| |
|
|
| The development of a bioactive nanocomplex formed along with polydeoxyribonucleotide and bone morphogenetic protein 2 (BMP2) provided synergistic abilities in angiogenesis and bone regeneration.
[Science Advances] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Investigators found that Trio was highly expressed in osteosarcoma than normal tissues and promoted the proliferation, migration, and invasion of osteosarcoma cells.
[Cell Death & Disease] |
|
|
|
| The authors analyzed the gene expression and outcome of 980 sarcoma patients from seven public datasets. The abundance of immune cells and the response to immunotherapy was calculated.
[Molecular Therapy-Oncolytics] |
|
|
|
| Investigators showed that compared with MSC-exosomes (exos) generated via 2D culture, 3D-exos showed enhanced anti-inflammatory effects in a ligature-induced model of periodontitis by restoring the reactive T helper 17 cell/Treg balance in inflamed periodontal tissues.
[International Journal of Oral Science] |
|
|
|
| Exosomes were extracted from the supernatant of the bone-marrow MSCs. The expression of the micro-RNA miR-93-3p was determined by qRT-PCR analysis.
[Bioengineered] |
| |
|
|
| Researchers indicated that KLF4 played opposing roles in platelet-derived growth factor receptor-β+ cells and α-smooth muscle actin+ cells and highlighted the importance of further studies of interactions between distinct mesenchymal cell types.
[Nature Communications] |
|
|
|
| Using unbiased transcriptome profiling of hypoxia-preconditioned MSCs and normoxic MSCs, scientists identified a lncRNA named lung cancer-associated transcript 1 (LUCAT1) under hypoxia.
[Molecular Therapy-Nucleic Acids] |
|
|
|
| Researchers reported a facile and efficient strategy for in vivo tracking the secretion of hepatocyte growth factor in MSCs during idiopathic pulmonary fibrosis therapy.
[Biomaterials Science] |
|
|
|
| A type 2 diabetes mellitus (T2DM) model was established through 28-week high-fat diet feeding resulting in T2DM-associated non-alcoholic fatty liver disease, followed by the injection of bone marrow MSCs.
[Stem Cell Research & Therapy] |
|
|
|
| Investigators manufactured neprilysin gene-enhanced human umbilical cord-derived MSCs and intravenously transplanted them in Aβ1-42-injected Alzheimer’s disease animal models.
[Stem Cells International] |
|
|
|
| The authors reported the use of MSCs for the production and delivery of Gastrin, a peptide hormone that is produced by intestinal cells and fetal islets and can increase β-cell mass, to promote protection from type 1 diabetes.
[Autoimmunity] |
|
|
|
|
| Scientists review MSC-based nanocomposite’s current approaches and compared their advantages and limitations for building effective regenerative medicines.
[European Journal of Pharmacology] |
|
|
|
| Investigators review the potential application of MSC extracellular vesicles as an emerging treatment strategy for optic neuritis by reviewing studies in multiple sclerosis and related disorders.
[Current Stem Cell Research & Therapy] |
|
|
|
|
| Sanford Health announced a stem cell trial expanding the use of adult-adipose derived stem cells in the use of osteoarthritis across five joints. The clinical trial, called the ENDURE trial, is the first of its kind study.
[Stanford Health] |
|
|
|
|
| February 6 – 9, 2022
Keystone Resort, Colorado, United States |
|
|
|
|
|
| | Ecole polytechnique fédérale de Lausanne – Lausanne, Canton of Vaud |
|
|
|
| | Karolinska Institute – Solna, Sweden |
|
|
|
| | Centre de recherche du CHUM – Montreal, Quebec, Canada |
|
|
|
| | Stanford University – Palo Alto, California, United States |
|
|
|
| University of Calgary – Calgary, Alberta, Canada |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
