 | | Vol. 14.02 – 18 January, 2022 |
| |
|
|
| The authors found that irisin pretreatment increased the cardiac homing of adipose tissue-derived MSCs administered by single and multiple intravenous injections to mice with myocardial ischemia-reperfusion by more than fivefold.
[Advanced Science] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Investigators reported that exosomes from MSCs administered as eye drops notably alleviated graft-versus-host disease-associated dry eye disease by suppressing inflammation and improving epithelial recovery in mice and humans.
[Science Advances] |
|
|
|
| Researchers showed that high-frequency MegaHertz-order mechanostimulation in the form of nanoscale amplitude surface reflected bulk waves were capable of triggering differentiation of human MSCs from various donor sources toward an osteoblast lineage.
[Small] |
|
|
|
| Scientists utilized a systems-based approach to compare MSCs from different genetic backgrounds that displayed differences in antibacterial activity.
[iScience] |
|
|
|
| The authors revealed that endometrial stromal cell ferroptosis in the ovarian endometrioma may have triggered cytokine secretion and promoted angiogenesis of adjacent lesions via paracrine actions to drive the development of endometriosis.
[Cell Death Discovery] |
|
|
|
| Investigators evaluated the potential of combining a natural and accessible biomaterial based on platelet poor plasma as a support for dental pulp stem cells and umbilical cord MSCs.
[Scientific Reports] |
|
|
|
| Researchers examined the role of B-cell CLL/lymphoma 9 (BCL9), which is downstream of hypoxia-inducible factor 1α and a Wnt/β-catenin transcriptional cofactor, in the osteo/odontoblastic differentiation of human dental pulp stem cells under hypoxic conditions.
[Scientific Reports] |
| |
|
|
| The authors screened the gene expression profiles of human bone marrow MSCs (BMSCs) from young and old donors and identified that elevation of the nucleosome assembly protein 1-like 2 (NAP1L2) expression was correlated with BMSC senescence and impaired osteogenesis.
[Aging Cell] |
|
|
|
| Scientists fabricated nanoparticles (NPs) using polylactic-co-glycolic acid loaded with the secretome (Sec) from MSCs to form MSC-Sec NPs.
[Journal of Nanobiotechnology] |
|
|
|
| The authors investigated the therapeutic effect of human amniotic MSCs combined with polyethylene glycol citrate-co-N-isopropylacrylamide mixed with gelatin (PPCNg) transplantation in promoting the regeneration of injured endometrium.
[Stem Cell Research & Therapy] |
|
|
|
| Researchers investigated the biological and cytological characteristics of rabbit nucleus pulposus MSCs (NPMSCs) and determined the effect of the growth and differentiation factor-5 on the differentiation of rabbit NPMSCs transduced with a lentivirus vector.
[European Journal of Medical Research] |
|
|
|
|
| The authors overview the current knowledge regarding the therapeutic efficacy of MSCs in systemic sclerosis (SSc), focusing on progresses reported in preclinical and clinical studies using MSCs, as well as challenges and future directions of MSC transplantation as a treatment option for patients with SSc.
[Clinical Reviews in Allergy & Immunology] |
|
|
|
| Scientists summarize the known interactions between MSCs, immune cells, and inflammatory cytokines following peripheral nerve injuries with a focus on the immunosuppressive role of MSCs.
[Stem Cell Research & Therapy] |
|
|
|
|
| Sorrento Therapeutics, Inc. announced receipt of clearance from ANVISA to proceed with a Phase IIa randomized, placebo-controlled study of intravenous allogeneic adipose-derived MSC to treat post COVID-19 “long haul” pulmonary compromise.
[Sorrento Therapeutics, Inc.] |
|
|
|
|
|
|
|
| | Mayo Clinic Florida Campus – Jacksonville, Florida, United States |
|
|
|
| | Boston Children’s Hospital – Boston, Massachusetts, United States |
|
|
|
| | National Institute of Health – Rockville, Maryland, United States |
|
|
|
| | Cedars-Sinai Regenerative Medicine Institute – Los Angeles, California, United States |
|
|
|
| | Centre de recherche du CHUM – Montreal, Quebec, Canada |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
