 | | Vol. 14.06 – 15 February, 2022 |
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| A wireless-electrical stimulation method was proposed to direct the neural differentiation of adipose-derived MSCs (ADMSCs) based on the electromagnetic effect using a graphene film as a conductive scaffold.
[Advanced Science] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers demonstrated how direct and indirect contact with allogenic MSCs improved regulatory T cells’ (Tregs) potential for accumulation of immunosuppressive adenosine and suppression of conventional T cell proliferation, making them more potent therapeutic tools.
[Nature Communications] |
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| Scientists synthesized surfactant-free amine-functionalized polystyrene (PS) nanoparticles (NPs) and PS-NPs with decreased crosslinking density without changing other factors, such as size, shape, and zeta potential and examined their effects on cell viability and physiology.
[Journal of Hazardous Materials] |
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| The authors developed four different 2D cell-based decellularized matrices and a 3D decellularized human trabecular-bone scaffold to evaluate bone marrow-MSC behavior.
[Journal of Tissue Engineering] |
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| Evaluations using human MSCs showed that pure polylactic acid (PLA) scaffolds exerted an osteoconductive effect, whereas PLA/hydroxyapatite scaffolds efficiently induced osteogenic differentiation of MSCs even in the absence of any classical osteogenic stimuli.
[Scientific Reports] |
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| Investigators showed that sliding hydrogels substantially accelerated cartilage matrix production by human MSCs in 3D compared to conventional chemical hydrogels with static/non-mobile crosslinks.
[Biophysical Journal] |
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| Researchers investigated whether miR-155 regulated glycolysis of psoriasis and the underlying mechanisms. Human dermal-derived MSCs were treated with miR-155 mimic or inhibitor, followed by assessments of cells proliferation, metabolism and inflammatory response.
[Journal of Dermatological Science] |
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| The roles of Ginsenoside Rb1 in cell viability, proliferation, apoptosis, osteogenic genes expression, and alkaline phosphatase activity of rat bone MSCs were evaluated.
[International Journal of Oral Science] |
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| Scientists created type I interferon (IFN)α-overexpressing MSCs. Upon direct injection into tumors, they found that these cells were powerful in eliminating several types of tumors.
[Oncogene] |
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| Investigators demonstrated that their composite scaffold with platelet-rich plasma/gelatin microspheres led to greater positive effects in promoting large bone defect repair.
[Tissue Engineering Part A] |
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| The authors investigated the effects of human adipose tissue- and umbilical cord-MSCs on neuropathic pain and its mechanisms using rat models of partial sciatic nerve ligation
[PLoS One] |
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| Researchers investigated the therapeutic effect of human umbilical cord MSCs on experimental autoimmune thyroiditis (EAT) and the underlying mechanisms by utilizing a porcine thyroglobulin-induced EAT rat model.
[Endocrine Journal] |
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| The authors consider both in vitro and in vivo studies that examine the role of Hedgehog in repair and discuss some of the challenges inherent in their interpretation.
[Bone Research] |
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| Current treatment methods for burn wounds are far from ideal, driving the need for tissue engineered solutions. Among various approaches, stem cell-based strategies are promising candidates for improving the treatment of burn wounds.
[Stem Cell Reviews and Reports] |
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| MTF Biologics has awarded more than $1 million in funding to nine researchers across the nation through its 2021 Extramural Research Grants Program. This year’s recipients are leading research in diverse areas including bone regeneration, orthopedic infection, and the toll of spinal epidural abscesses.
[MTF Biologics] |
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| 2022-03-20-2022-03-25 |
Vienna, Austria |
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| | Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore |
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| | University of Washington – Seattle, Washington, United States |
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| | Wayne State University School of Medicine – Detroit, Michigan, United States |
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| | Nanyang Technological University – Singapore, Singapore |
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| | Mayo Clinic Florida Campus – Jacksonville, Florida, United States |
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