 | | Vol. 14.08 – 1 March, 2022 |
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| Autochthonous murine models of pancreatic cancer (PC) and co-implanted allografts of murine PC cell lines with adipose-derived MSCs were used to assess the role of Muc5ac in stromal heterogeneity.
[Gastroenterology] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Investigators analyzed the circRNA expression profile of five samples of bone marrow MSCs in osteonecrosis of the femoral head (ONFH) and five samples of control by using circular RNA microarray assays.
[Molecular Therapy-Nucleic Acids] |
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| The authors investigated the impact of oxygen on mitochondrial dynamics in placental MSCs that were vital for proper placental development.
[Cell Death & Disease] |
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| Researchers constructed a bionic biphasic composite scaffold with on-demand osteochondrogenic factors. Kartogenin and extractive MSCs were introduced into a mPEG-block-poly(L-valine) thermogel set as the upper layer to accelerate cartilage repair.
[Biomaterials Science] |
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| Rat bone marrow-derived MSCs and human umbilical vein endothelial cells (HUVECs) were co-cultured onto scaffolds fabricated by the authors to enhance vascularization for bone tissue regeneration.
[Colloids and Surfaces B-Biointerfaces] |
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| Based on the urgent need for improved treatments for undifferentiated pleomorphic sarcoma and malignant peripheral nerve sheath tumors and the limited cellular models available, investigators generated additional cell lines to study these rare cancers.
[Laboratory Investigation] |
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| Scientists established various human cell lines with human artificial chromosomes/mouse artificial chromosomes that harbored a gene-loading site via microcell-mediated chromosome transfer.
[Scientific Reports] |
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| Investigators utilized bone morphogenetic protein (BMP) inhibitors DMH1, JL5, and Ym155 to examine the role of BMP signaling on the growth of glioblastomas.
[Molecular and Cellular Biochemistry] |
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| Researchers showed that a five amino acid oligopeptide promoted osteogenesis by binding to the integrin α5 subunit and thereby activating FAK signaling.
[Bone Research] |
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| The authors explored the mechanism of human umbilical cord MSCs-derived extracellular vesicles loaded with miR-223 on myocardial infarction.
[Genomics] |
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| Scientists examined whether haem oxygenase-1 (HO-1) could enhance the immunosuppressive effects of bone marrow MSCs (BMMSCs) on the rejection of transplanted liver allografts in rats.
[Scientific Reports] |
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| Using MSCs from p62 knockout adult mice, researchers investigated the effect of p62 on MSC survival and bone-forming molecule cascades.
[General and Comparative Endocrinology] |
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| The authors summarize and discuss the rational construction of versatile biomaterials with bone therapeutic and regenerative functions.
[Bone Research] |
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| Scientists discuss various strategies to consistently maintain or enhance the immunomodulatory potency of MSCs during ex vivo expansion, which will enable the manufacture of allogeneic MSC banks that have high potency and low variability.
[Cytotherapy] |
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| Much extrapolation work is needed to validate that electroactive and electroconductive scaffolds can promote neurogenesis of dental and oral-derived stem cells, which would thus facilitate clinical applications in neuroregeneration therapy.
[International Journal of Oral Science] |
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| Ageless Biotech, Inc. acquired a US FDA Investigational New Drug Application for the treatment of osteoarthritis of the knee, using minimally manipulated adipose derived stem cells without enzymes or other chemicals through a proprietary process of a well-known method referred to as stromal vascular fraction.
[Ageless Biotech, Inc. (PR Newswire, Inc.)] |
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| Revotek announced that it has received clearance from the National Health Commission of China to begin a clinical study in the West China Hospital, Chengdu, with its first stem cell 3D bioprinting product, REVOVAS.
[Revotek (PR Newswire, Inc.)] |
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| City of Hope’s Department of Stem Cell Biology and Regenerative Medicine has received a $4.9 million grant to train the next generation of scientific leaders in basic stem cell research and its translation into novel, lifesaving treatments.
[City of Hope] |
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| April 7 – April 9, 2022
Rome, Italy & Virtual |
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| | University of Edinburgh – Edinburgh, Scotland, United Kingdom |
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| | National Institute for Health and Medical Research – Paris, France |
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| | University of Lausanne – Lausanne, Switzerland |
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| | Singapore-MIT Alliance for Research and Technology (SMART) Centre – Singapore, Singapore |
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| | University of Lausanne – Lausanne, Switzerland |
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Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
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Pancreatic Cell News
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