 | | Vol. 14.13 – 5 April, 2022 |
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| Exosomes from the conditioned medium of gingival MSC were isolated by ultracentrifugation and were injected into the vitreous of mice.
[Biomaterials] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers evaluated the effects of a selective G9a histone methyltransferase inhibitor on Ewing sarcoma metastatic process.
[Oncogene] |
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| Investigators found that N-(3-aminopropyl)-2–N-(2-thienylmethyl) benzamide hydrochloride (AMTB) suppressed osteosarcoma cell proliferation, metastasis and induced cellular apoptosis.
[Cell Death & Disease] |
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| To identify MSC subpopulations and clarify their relationships, scientists performed cell mapping of bone marrow-derived MSCs through single-cell RNA sequencing.
[Experimental and Molecular Medicine] |
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| The authors fabricated a multilayered nanocomposite scaffold containing the wild type of Type I collagen (Col I) with endogenous magnetic property to promote osteogenesis in rat adipose-derived stem cells with the minimum requirement of osteogenic differentiation medium.
[Stem Cell Research & Therapy] |
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| Scientists demonstrated a simple method to perform layer by layer assembly on microcarriers to create multilayers of heparin and collagen and further demonstrated that these multilayers had a positive effect on human MSC viability after 48 hours of culture.
[Biotechnology Journal] |
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| Researchers investigated the role of amniotic fluid-MSCs in preventing versus treating the hyperoxia-induced lung fibrosis in rats.
[Stem Cell Research & Therapy] |
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| The authors investigated the effects of rapamycin on the proangiogenic ability of senescent human umbilical cord MSCs.
[Acta Pharmacologica Sinica] |
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| Scientists described a novel subset of renal perivascular MSCs that expressed Meflin, a glycosylphosphatidylinositol-anchored protein that was recently identified as a marker of fibroblasts essential for cardiac tissue repair.
[Scientific Reports] |
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| Researchers tested the safety, tolerability and efficacy of human umbilical cord MSCs for the treatment of pneumonia-induced sepsis through a single-center, randomized single-blind parallel-group, placebo-controlled trial.
[BMJ Open] |
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| Ophthalmologists are now working closely with basic researchers to incorporate new technology areas with a synergy that is anticipated to realize the practical application of stem cell-based therapy for retinal degeneration.
[Trends in Molecular Medicine] |
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| The authors summarize the current approaches of MSC pre-activation and further classify, analyzed the scientific principles and main characteristics of these manipulations, and describe the pros and cons of individual pre-activation strategies.
[Stem Cell Research & Therapy] |
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| BioRestorative Therapies, Inc. announced that it has completed testing and certification of its clinical grade cell therapy manufacturing facility. The facility will support BioRestorative’s clinical manufacturing needs for its active Phase II clinical trial targeting chronic lumbar disc disease.
[BioRestorative Therapies, Inc. (GlobeNewswire, Inc.)] |
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| May 9 – 12, 2022
Montreal, Quebec, Canada |
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| | Baylor College of Medicine – Houston, Texas, United States n |
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| | Novo Nordisk – Fremont, California, United States |
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| | Cancer Research UK Manchester Institute – Manchester, England, United Kingdom |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Genentech, Inc. – South San Francisco, California, United States |
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