 | | Vol. 14.14 – 12 April, 2022 |
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| A lipopolysaccharide-loaded photoresponsive cryogel porous microcarrier for MSCs delivery and colonization was presented to promote defect liver regeneration.
[Small] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| A protocol was complemented through a novel in silico workflow that allowed for in-depth estimation and potential optimization of the quality of generated muscle tissue, based on the transcriptomes of transdifferentiated cells.
[Cellular and Molecular Life Sciences] |
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| Scientists explored miRNA profiles of CB-MSCs during differentiation into motor neuron-like cells.
[Scientific Reports] |
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| In vitro, Jagged1 was found to be activated by Notch1 in MSCs, resulting in the RBP-Jκ-dependent expression of Jagged1 mRNA, a response that was blocked by Notch1 inhibition.
[BMC Pulmonary Medicine] |
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| In vitro studies showed, wharton’s jelly-derived-MSCs that differentiated in the 3D culture had strong properties of insulin-producing cells such as islet-like cells.
[Artificial Organs] |
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| Investigators used an organotypic model of wound healing and they seeded keratinocytes on an adipose-derived MSC-induced dermal matrix. Conventional hematoxylin–eosin stain and immunohistochemistry staining for Ki67, p63 and pan-keratins were performed at different timepoints.
[Microscopy Research and Technique] |
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| | Researchers studied the proferroptosis effect and mechanism of MSC-ex in hepatic stellate cells. MSC-ex were collected and purified from human umbilical cord MSCs.
[Cell Death & Disease] |
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| The authors evaluated the therapeutic potential of MSCs isolated from menstrual blood as ready-to-use allo-MSCs in multiple sclerosis by application in its animal model experimental autoimmune encephalomyelitis.
[Stem Cell Research & Therapy] |
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| MSCs were encapsulated in the 3D printable GelMA ink, and their biological properties were assessed in vitro to evaluate their potential for cell delivery application.
[Journal of Biomedical Materials Research Part B-Applied Biomaterials] |
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| Investigators embedded a scaffold material containing a conditioned medium of MSCs (MSC-CM) pretreated with IFN-γ and TNF-α and reconfirmed that cell migration and activation were superior to that in the presence of MSC-CM in vivo.
[PLoS One] |
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| Scientists review the different works reported in the literature that have used secretomes of Schwann cells or MSCs in the treatment of peripheral nerve injuries in experimental models.
[Experimental Neurology] |
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| The authors present the current landscape of the field and highlights some interesting findings on MSC-derived extracellular vesicles in the context of COVID-19, including in silico, in vitro, in vivo and case reports.
[Journal of Tissue Engineering and Regenerative Medicine] |
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| Investigators present a guide for pre-clinical and clinical studies on the role of MSCs-conditional media in skin wound healing.
[International Wound Journal] |
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| Canada’s Stem Cell Network announced the launch of IGNITE 2022-2025, its three-year strategic plan funded by the Government of Canada through a $45 million Budget 2021 commitment, starting April 1st, 2022.
[Stem Cell Network] |
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| September 19 – 20, 2022
Vejle, Denmark |
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| | Johns Hopkins University – Baltimore, Maryland, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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| | Novo Nordisk – Fremont, California, United States |
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| | Cancer Research UK Manchester Institute – Manchester, England, United Kingdom |
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| | Baylor College of Medicine – Houston, Texas, United States |
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