 | | Vol. 14.20 – 24 May, 2022 |
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| Scientists established a foundation towards a clinical trial of hydrogel encapsulated bifunctional MSCs in primary and recurrent glioblastoma patients.
[Nature Communications] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Using osteosarcoma cells, the authors found that in addition to its known localizations on microtubules and the plasma membrane, MARK2 also associated with the actomyosin cytoskeleton and focal adhesions.
[Current Biology] |
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| Researchers determined the link between inflammation and cartilage mineralization by targeting Sirtuin 1 and lymphoid enhancer binding factor 1 (LEF1), both reported to have contrasting effects on cartilage.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| A methacrylate gelatin and methacrylate sericin hydrogel with human umbilical cord mesenchymal stem cells encapsulation was designed for facilitating endometrial regeneration and fertility restoration through in situ injection.
[Bioengineering & Translational Medicine] |
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| MSCs were isolated from human placental membrane, mammary adipose tissue and dental pulp and subjected to RT-PCR, Western blotting and mass spectrometry to investigate the expression of myoglobin.
[Stem Cell Research & Therapy] |
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| Organoids from the epithelioid sarcoma could be serially cultured and maintained in collagen type 1 gels for more than three passages. Developed orthotopic tumor xenografts were detected in the NSG mice.
[Frontiers in Oncology] |
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| Investigators elucidated the mechanisms regarding extracellular vesicle-packaged microRNA-22-3p from M2 macrophages in the osteogenic differentiation of MSCs in ankylosing spondylitis.
[Cell Death Discovery] |
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| Scientists tested the mechanosensing properties of three human homogeneous MSC lines derived from induced pluripotent stem cells generated using a fully automated platform.
[Scientific Reports] |
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| Investigators evaluated the long noncoding RNA and mRNA expression profiles of interleukin-1β-stimulated synovial fluid-derived MSCs.
[Scientific Reports] |
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| Researchers demonstrated the synergistic effects of fluid shear stress and adhesion morphology in directing the fate of MSCs, and these effects may be adopted to design bio-functional substrates for cell transplantation in tissue engineering.
[Journal of Biomedical Materials Research Part A] |
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| Bone marrow-derived MSCs were collected from type 2 diabetes rat model and the protein and gene expression of special AT-Rich Binding protein 1 (SATB1), and osteospecific genes were evaluated post osteogenic induction.
[Oral Diseases] |
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| The oral delivery of stem-cell-loaded hydrogel microcapsules enhanced MSC survival and retention in the hostile stomach environment due to the intermediate oil layer and low value of the overall stiffness.
[Journal of Controlled Release] |
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| Researchers investigated the differentiation of Wharton’s jelly-derived MSCs into pancreatic islet-insulin producing cells on silk/gelatin nanofibers as a 3D scaffold.
[Gene] |
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| Scientists focus on the close relationship between the circadian clock and MSC l fate decisions in the skeletal system.
[Stem Cell Research & Therapy] |
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| The authors describe the existing evidence of cross talk between Hippo signaling pathway key molecules and the process of EMT, with emphasis on the role of Hippo—EMT interplay in cancer.
[Molecular Biology Reports] |
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| Calidi Biotherapeutics, Inc. has been granted a new patent by the US Patent and Trademark Office related to its proprietary SuperNova (SNV) technology platform. The SNV platform is composed of allogeneic, adipose-derived MSCs loaded with an oncolytic agent.
[Calidi Biotherapeutics, Inc.] |
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| June 15 – 18, 2022
San Francisco, California, United States |
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| | TU Dresden – Dresden, Germany |
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| | University of Leeds – Leeds, United Kingdom |
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| | The University of British Columbia – Vancouver, British Columbia, Canada |
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| | Wayne State University – Detroit, Michigan, United States |
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| | Baylor College of Medicine – Houston, Texas, United States |
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