 | | Vol. 14.30 – 2 August, 2022 |
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| Investigators reported a new conductive hybrid film that could guide osteogenic differentiation of human adipose-derived MSCs via electrically controlled mRNA delivery.
[Nano Research] |
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| PUBLICATIONSRanked by the impact factor of the journal |
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| Bone morphogenetic protein-2 (BMP-2) peptides presented in soluble and immobilized form increased alkaline phosphatase expression in MSCs cultured on 2D and encapsulated in 3D norbornene–tetrazine hydrogels.
[Frontiers in Biomaterials Science] |
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| Scientists reported the therapeutic actions of human adipose-derived MSCs in nephritis, focusing on cellular dynamics and multi-organ networks.
[Communications Biology] |
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| The authors focused on the epigenetic mechanisms in MSC migration. TGF-β1 stimulated bone marrow MSCs to promote cell migration at lesion sites in vitro and in vivo.
[Cell Death Discovery] |
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| Scientists developed dual gene modification of bone marrow-derived MSCs (BMSCs) and found that the migration and immunomodulatory activity of genetically engineered BMSCs were significantly enhanced compared to their natural counterparts.
[Molecular Immunology] |
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| Zein, a plant protein, was utilized to make patterned surface mimicking the extracellular matrix to assist the attachment and proliferation of stem cells.
[Journal of Biomedical Materials Research Part B-Applied Biomaterials] |
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| Researchers found that safrole oxide could induce bone marrow MSC differentiation into 5-hydroxytryptamine (5-HT) neuron-like cells.
[In Vitro Cellular & Developmental Biology – Animal] |
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| | Pbx1, Rfx3, Pdx1, Ngn3, Pax4 and MafA were used to form a six-gene combination to efficiently reprogram adipose MSCs (aMSCs) into reprogrammed aMSCs-derived islet β-cells.
[Stem Cell Research & Therapy] |
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| TGF-β1-induced hepatic stellate cell-T6 and CCl4-induced hepatic fibrosis rats were treated with bone marrow MSCs.
[Stem Cell Research & Therapy] |
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| The authors discuss the cell-protective and anti-inflammatory characteristics of bone marrow-MSCs to boost highly functional insulin-producing cells in vitro and in vivo.
[Stem Cell Research & Therapy] |
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| Investigators discuss the two opposite roles of residential MSCs and external MSCs in fibrotic diseases, and summarize the current perspective of the therapeutic mechanism of MSCs in fibrosis, through both laboratory study and clinical trials.
[Acta Pharmacologica Sinica] |
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| The University of Florida (UF) Center for Regenerative Medicine announced the launch of a clinical trial to test safe dosages of umbilical cord-derived stem cells in the treatment of two debilitating autoimmune disorders.
[University of Florida Health] |
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| October 3 – 5, 2022
Vancouver, British Columbia, Canada |
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| | German Cancer Research Center in the Helmholtz Association – Dresden, Germany |
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| | Essen University Hospital – Essen, Germany |
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| | Sanford Research – Sioux Falls, South Dakota, United States |
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| | The Chinese University of Hong Kong – Hong Kong, China |
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| Michigan Medicine – Ann Arbor, Michigan, United States |
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