CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Baculovirus-Transduced Bone Marrow Mesenchymal Stem Cells for Systemic Cancer Therapy The findings suggest that baculoviral transduction of mesenchymal stem cells is an attractive option to generate targeting vehicles for systemic cancer therapy. [Gene Ther] Intranigral Transplantation of Epigenetically-Induced BDNF-Secreting Human Mesenchymal Stem Cells: Implications for Cell-Based Therapies in Parkinson´s Disease The aim of the present study was to characterize signals and/or molecules that regulate brain-derived neurotrophic factor (BDNF) protein expression/delivery in human mesenchymal stem cell (hMSC) cultures and evaluate the effect of epigenetically generated BDNF-secreting hMSC on the intact and lesioned substantia nigra. [Biol Blood Marrow Transplant] Long-Term Efficacy and Safety of Human Umbilical Cord Mesenchymal Stromal Cells in Rotenone-Induced Hemiparkinsonian Rats In this study, researchers investigated migration, therapeutic, tumorigenesis and epileptogenic effects of human umbilical cord mesenchymal stromal cells one year after transplantation to rotenone-induced hemiparkinsonian rats. [Biol Blood Marrow Transplant] Regulation of Mesenchymal Stem Cell Activity by Endothelial Cells Researchers have determined the effects of paracrine factors secreted by human umbilical vein endothelial cells (HUVEC) on mesenchymal stem cell survival, proliferation and differentiation by using an optimised, serum-free HUVEC-conditioned medium. [Stem Cells Dev] Glial Cell Line-Derived Neurotrophic Factor-Secreting Genetically Modified Human Bone Marrow-Derived Mesenchymal Stem Cells Promote Recovery in a Rat Model of Parkinson’s Disease Here, researchers report the effects of glial cell line-derived neurotrophic factor-releasing Notch-induced human bone marrow-derived mesenchymal stem cells grafted into striatum of the 6-hydroxydopamine progressively lesioned rat model of Parkinson’s disease. [J Neurosci Res] Circulating Plastic Adherent Mesenchymal Stem Cells in Aged Hip Fracture Patients This initial study indicates mobilization of mesenchymal stem cells (MSCs) into the circulation in response to fracture, even in very old patients, while circulating MSCs were not detectable before or after elective total hip arthroplasty. [J Orthop Res] Biocomposites Electrospun with Poly(Epsilon-Caprolactone) and Silk Fibroin Powder for Biomedical Applications Researchers fabricated a biocomposite using poly(epsilon-caprolactone) and silk fibroin powder, which has good biocompatibility and mechanical properties. The biocompatibility of the biocomposite was evaluated in a culture of bone-marrow-derived rat mesenchymal stem cells. [J Biomater Sci Polym Ed] Conditioned Media Enhance Osteogenic Differentiation on Poly(L-lactide-co-epsilon-caprolactone)/Hydroxyapatite Scaffolds and Chondrogenic Differentiation in Alginate The objectives of this study were to determine the effects of chondrocyte conditioned medium (CM) on the osteogenic differentiation of mesenchymal stem cells (MSCs) cultured on poly(L-lactide-co-epsilon-caprolactone)/hydroxyapatite scaffolds and to determine the effect of osteoblast CM on the chondrogenic differentiation of MSCs cultured in alginate. [J Biomater Sci Polym Ed] Safety Concern between Autologous Fat Graft, Mesenchymal Stem Cell and Osteosarcoma Recurrence Researchers report a case of a late local recurrence of osteosarcoma which occurred 13 years after the initial pathology and 18 months after a lipofilling procedure. These observations and results raise the question of whether autologous fat grafting is a safe reconstructive procedure in a known post neoplasic context. [PLoS ONE]
|
|
POLICY NEWS FDA Takes Issue with Genetic Tests from 23andMe, Four Other Firms The Food and Drug Administration has put five genetic test makers on notice that they must get federal approval before marketing their products for use by consumers. [Food and Drug Administration, United States] NIH Chief Collins Faces Stem Cell Donation Dilemma The NIH Advisory Committee to the Director, which advises NIH chief Francis Collins on whether lines meet the Obama ethics guidelines, faced the decision on whether 53 more stem cell lines should be added to that total. [National Institutes of Health, United States] NIH Researchers Explore How Healthy, Young Adults View the Role Genetics Plays in Improving Health Most healthy young adults place greater emphasis on health habits than on genetic risk factors when considering what causes common diseases, a research team from the National Human Genome Research Institute and the Henry Ford Health System in Detroit has found. [National Institutes of Health, United States] Enhancing Peer Review: Advance Notice on Post-Submission Application Materials for NIH Training and Related Applications (NOT-OD-10-104) [National Institutes of Health, United States] PFINDR: Phenotype Finder IN Data Resources: A Tool to Support Cross-Study Data Discovery Among NHLBI Genomic Studies (UH2/UH3) (RFA-HL-11-020) [National Institutes of Health, United States] Clinical Trials for Medicines Section Updated [Medicines and Healthcare Products Regulatory Agency, United Kingdom] Advertising and Supply of Therapeutic Goods to Complementary Healthcare Professionals: Schedule 1 to the Therapeutic Goods Regulations [Therapeutic Goods Administration, Australia] Increased Transparency of the Prescription Medicine Regulatory Process [Therapeutic Goods Administration, Australia]
|
|
EVENTS International Society for Stem Cell Research (ISSCR) 8th Annual Meeting June 16-19, 2010 San Francisco, United States Worldwide Innovative Networking (WIN) Symposium in Personalized Cancer Medicine July 7-9, 2010 Paris, France Translational Cancer Medicine 2010 – USA July 11-14, 2010 San Francisco, United State 2nd International Conference on Cellular and Molecular Bioengineering (ICCMB2) August 2-4, 2010 Singapore City, Singapore Select Biosciences 3rd Annual Stem Cells Europe Conference August 24-25, 2010 Edinburgh, Scotland Select Biosciences Inaugural Cellular Therapy Summit August 24-25, 2010 Edinburgh, Scotland United Kingdom National Stem Cell Network (UKNSCN) 3rd Annual Scientific Conference July 12-14, 2010 Nottingham, United Kingdom Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010 September 15-17, 2010 Sydney, Australia 5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010 October 5-7, 2010 Hannover, Germany 2010 American Society for Matrix Biology (ASMB) Meeting October 24-27, 2010 Charleston, United States 52nd American Society of Hematology (ASH) Annual Meeting and Exposition December 4-7, 2010 Orlando, United States Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference December 5-8, 2010 Orlando, United States Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Senior Scientist – Magnetic Cell Separation (STEMCELL Technologies) Business Development Manager Europe – Cell Therapy Products (Pall Corporation) Manager/Sr. Manager, Therapeutic Cell Solutions, Process Development (Lonza) Sr. Product Support and Training Specialist (CardianBCT) Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Mesenchymal Cell News. Visit here to post your career opportunities.
Have we missed an important article or publication in Mesenchymal Cell News? Click here to submit! Comments or Suggestions? Email info@connexoncreative.com with your feedback. |
| |
|