SCIENCE NEWS A Smart Use for Wisdom Teeth: Making Stem Cells For most people, wisdom teeth are not much more than an annoyance that eventually needs to be removed. However, a new study shows that wisdom teeth contain a valuable reservoir of tissue for the creation of stem cells; thus, everyone might be carrying around his or her own personal stem cell repository should he or she ever need some. [Press release from EurekAlert! discussing online prepublication to be published in the Journal of Biological Chemistry]
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CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Periodontal Regeneration Using Engineered Bone Marrow Mesenchymal Stromal Cells Researchers hypothesized that bone marrow mesenchymal stromal cells are able to sense biological cues from the local microenvironment and organize appropriately to contribute to the regeneration of both soft and hard periodontal connective tissues. [Biomaterials] Paracrine Factors of Multipotent Stromal Cells Ameliorate Lung Injury in an Elastase-induced Emphysema Model The findings suggest that paracrine factors derived from multipotent stromal cells is the main mechanism for the protection of lung tissues from elastase injury. [Mol Ther] Human Cardiac and Bone Marrow Stromal Cells Exhibit Distinctive Properties Related to Their Origin Objective of the present work is the comparison of in vitro and in vivo properties of adult human cardiac stromal cells to those of syngeneic bone marrow mesenchymal stromal cells. [Cardiovasc Res] Mesenchymal Stem Cells Stimulate Endogenous Neurogenesis in the Subventricular Zone of Adult Mice This is the first study to show that mesenchymal stem cells might interfere with the tight regulation of the subgranular zone, independent of the induced brain lesion. [Stem Cell Rev] Atorvastatin Prevents Mesenchymal Stem Cells from Hypoxia and Serum-Free Injury Through Activating AMP-Activated Protein Kinase Researchers hypothesized that atorvastatin could protect mesenchymal stem cells from hypoxia and serum-free injury through AMP-activated protein kinase-endothelial nitric oxide synthase pathway. [Int J Cardiol] Mesenchymal Stem Cells Display Hepato-Protective Activity in Lymphoma Bearing Xenografts The data suggest that hyaluronan-embedded mesenchymal stem cells exert anti-lymphoma activity by ameliorating hepatic functionality. [Invest New Drugs] Anti-Fibrotic Effect of Chorionic Plate-Derived Mesenchymal Stem Cells Isolated from Human Placenta in a Rat Model of CCl4-Injured Liver: Potential Application to the Treatment of Hepatic Diseases Here, researchers evaluated the therapeutic effect of chorionic plate-derived mesenchymal stem cells isolated from human placenta and transplanted into rats with carbon tetrachloride (CCl4)-injured livers. [J Cell Biochem] Maintenance and Expansion of Hematopoietic Stem/Progenitor Cells in Biomimetic Osteoblast Niche In this study, researchers employed bio-derived bone scaffold and composited with the marrow mesenchymal stem cell induced into osteoblast to replicate a “biomimetic niche”. [Cytotechnology] INDUSTRY NEWS STEMSOFT® Software Inc. Licenses StemLab® Software to Arizona’s Celebration Stem Cell Centre STEMSOFT Software Inc., the leading provider of software solutions for the cell therapy and transplant community, is pleased to announce the licensing of StemLab, the leading cell therapy and cord blood banking laboratory software, to the Celebration Stem Cell Centre in Gilbert, Arizona. [STEMSOFT Software Inc. Press Release] AstraZeneca and UCL Join Forces in Sight-Related Stem Cell Medicine AstraZeneca and University College London (UCL) have entered into a collaboration to develop regenerative medicines for diabetic retinopathy. [University College London Press Release] Forbion Capital Partners Raises EUR190 Million for New Investments Forbion Capital Partners, a leading investment firm dedicated to the life science sector, announced the final closings of both FCF I Co-Invest Fund and of FCF II, raising a total of more than EUR190 million ($240 million). [Forbion Capital Partners Press Release] NIH Awards $8 Million to UT Southwestern to Study Metabolism, Obesity-Related Inflammation An $8 million grant from the National Institutes of Health will enable UT Southwestern Medical Center to investigate how fat tissue “talks” to the brain and the liver to promote inflammation-related disorders such as diabetes, heart disease and obesity. [UT Southwestern Medical Center Press Release] Lilly to Invest Up to $150 Million in Venture Capital Eli Lilly & Co., facing competition from cheaper copies of its top-selling drug next year, plans to invest as much as $150 million in three venture capital funds to aid development of new medicines. [Bloomberg]
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POLICY NEWS NIH Expands Network Focused on How Genes Affect Drug Responses [National Institutes of Health, United States] National Institute of Biomedical Imaging and Bioengineering; Notice of Closed Meeting (FR Doc. 2010-22327) [National Institutes of Health, United States] National Heart, Lung, and Blood Institute; Notice of Closed Meeting (FR Doc. 2010-22314) [National Institutes of Health, United States] National Center for Research Resources; Notice of Closed Meetings (FR Doc. 2010-22529) [National Institutes of Health, United States] Notice of Correction: Application Due Date for RFA-HG-10-012, Revolutionary Genome Sequencing Technologies – The $1000 Genome (R01) and RFA-HG-10-013, Revolutionary Genome Sequencing Technologies – The $1000 Genome (R21) (Notice Number:NOT-HG-10-021) [National Institutes of Health, United States] Knockout Mouse Production and Cryopreservation (U42) (RFA-RM-10-013) [National Institutes of Health, United States] Knockout Mouse Phenotyping Project Database (U54) (RFA-RM-10-012) [National Institutes of Health, United States] Knockout Mouse Phenotyping (U54) (RFA-RM-10-011) [National Institutes of Health, United States] Enhancing Peer Review: Reminder of and Correction to Previous Notice on A2 Resubmission Opportunities for Eligible Applications (NOT-OD-10-135) [National Institutes of Health, United States] Notice of Correction to RFA-AG-11-010, Basic Research on Self-Regulation (R21) (NOT-AG-10-011) [National Institutes of Health, United States] Agenda for the Public Workshop on Cell and Gene Therapy Clinical Trials in Pediatric Populations [Food and Drug Administration, United States]
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EVENTS (Listed by Date) Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Asia Pacific 2010 September 15-17, 2010 Sydney, Australia 5th Annual Germany Society for Stem Cell Research September 30-October 2, 2010 Lübeck, Germany 2010 World Stem Cell Summit October 4-6, 2010 Detroit, United States 5th World Congress on Preventative and Regenerative Medicine (WCRM) 2010 October 5-7, 2010 Hannover, Germany 17th Annual Meeting German Society for Gene Therapy (DG-GT e.V.) October 6-9, 2010 Munich, Germany bone-tec 2010 – International Bone-Tissue Engineering Congress October 7-10, 2010 Hannover, Germany The NYSCF Fifth Annual Translational Stem Cell Research Conference October 12-13, 2010 New York, United States International Federation of Adipose Therapeutics & Science (IFATS) 2010 Conference October 22-24, 2010 Dallas, United States 2010 American Society for Matrix Biology (ASMB) Meeting October 24-27, 2010 Charleston, United States Stem Cell Society Singapore Symposium 2010 November 2-3, 2010 Singapore 52nd American Society of Hematology (ASH) Annual Meeting and Exposition December 4-7, 2010 Orlando, United States Tissue Engineering & Regenerative Medicine International Society (TERMIS) – North America 2010 Annual Conference December 5-8, 2010 Orlando, United States Epithelial Plasticity and Epithelial to Mesenchymal Transition (A8) January 21-26, 2011 Vancouver, Canada Phacilitate 7th Annual Cell & Gene Therapy Forum 2011 January 24-26, 2011 Washington DC, United States Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States Stem Cells, Cancer and Metastasis (C4) March 6-11, 2011 Keystone, United States NEW Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference June 7-10, 2011 Granada, Spain Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community.
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