CURRENT PUBLICATIONS (Ranked by Impact Factor of the Journal) Linking Transgene Expression of Engineered Mesenchymal Stem Cells and Angiopoietin-1-induced Differentiation to Target Cancer Angiogenesis The purpose of this study was to specifically target tumor angiogenesis by linking transgene expression of engineered mesenchymal stem cells to angiopoietin-1-induced differentiation. [Ann Surg] Selective Venous Catheterization for the Localization of Phosphaturic Mesenchymal Tumors Tumor-induced osteomalacia is characterized by renal phosphate wasting, hypophosphatemia, aberrant Vitamin D3 metabolism, and is caused by FGF23-producing mesenchymal tumors, which are often difficult to locate. Researchers investigated the utility of selective venous sampling in tumor localization. [J Bone Miner Res] Biphasic Effects of Transforming Growth Factor-Beta on Bone Morphogenetic Protein-Induced Osteoblast Differentiation In order to identify kinases mediating bone morphogenetic protein (BMP)-induced osteoblast differentiation, researchers performed a siRNA screen to find kinases modulating BMP6-induced alkaline phosphatase (ALP) activity. [J Bone Miner Res] Urokinase Receptor Mediates Mobilization, Migration, and Differentiation of Mesenchymal Stem Cells Multipotent mesenchymal stem cells (MSCs) have regenerative properties and are recognized as putative players in the pathogenesis of cardiovascular diseases. The underlying molecular mechanisms remain, however, sparsely explored. This study was designed to elucidate a probable role for the multifunctional urokinase (uPA)/urokinase receptor (uPAR) system in MSC regulation. [ Cardiovasc Res] Mesenchymal Stem Cell Transplantation Modulates Neuroinflammation in Focal Cerebral Ischemia: Contribution of Fractalkine and IL-5 In this study, researchers have investigated the neuroimmunomodulatory functions of human mesenchymal stem cells, transplanted in rat focal ischemia model of transient middle cerebral artery occlusion. [Neurobiol Dis] Role of TRX 1 and TRX2 on Proliferation of Human Adipose Tissue-Derived Mesenchymal Stem Cells To investigate the role of thioredoxin (TRX)1 and TRX2 in human adipose tissue-derived mesenchymal stem cells (hADSC), researchers modulated TRX1 and TRX2 expressions in hADSC using a lentiviral gene transfer system and siRNA technique. [Stem Cells Dev] Tubular Perfusion System for the Long-Term Dynamic Culture of Human Mesenchymal Stem Cells To enhance nutrient transport researchers have developed a novel bioreactor, the tubular perfusion system, to culture human mesenchymal stem cells in three-dimensional scaffolds. [Tissue Eng Part C Methods] Optimization of Culture Conditions for the Expansion of Umbilical Cord Derived MSC Like Cells Using Xeno-Free Culture Conditions First isolated from bone marrow, mesenchymal stem or stromal cells (MSC) were shown to be present in several post-natal and extraembryonic tissues as well as in a large variety of fetal tissues (e.g. fatty tissue, dental pulp, placenta, umbilical cord blood and tissue). In this study, an optimized protocol for the expansion of MSC-like cells from whole umbilical cord tissue under xeno-free culture conditions is proposed. [Tissue Eng Part C Methods]
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INDUSTRY NEWS CIRM Governing Board Re-Elects Robert Klein as Chair, Senator Art Torres and Duane Roth as Co-Vice Chairs The Governing Board of the California Institute for Regenerative Medicine (CIRM), the state stem cell agency created by proposition 71, voted to re-elect current chair Robert Klein. [California Institute for Regenerative Medicine Press Release] Cryo-Save to Launch Cryo-Lip in the U.S. Cryo-Save Group N.V., Europe’s leading stem cell bank, announced that it intends to launch Cryo-Lip in the United States in 2011, after the successful introduction of the service in Europe during 2010. Cryo-Save is one of the first in the world that offers cryostorage of adult mesenchymal stem cells from fatty tissue for use by patients undergoing a surgical procedure. [Cryo-Save Group N.V. Press Release]
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EVENTS (Listed by Date) Keystone Symposia: Epithelial Plasticity and Epithelial to Mesenchymal Transition January 21-26, 2011 Vancouver, Canada 5th Annual Stem Cells and Regenerative Medicine World Congress January 24-25, 2011 San Diego, United States Phacilitate 7th Annual Cell & Gene Therapy Forum 2011 January 24-26, 2011 Washington, D.C., United States Keystone Symposia: Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States Stem Cell Research Forum of India 2nd Annual Meeting February 8-11, 2011 Bangalore, India 1st Annual Clinical Meeting of the Cell Society February 18-19, 2011 La Jolla, United States SMi Stem Cells 2011 – Innovation and Commercialisation February 23-24, 2011 London, United Kingdom Cell Culture World Congress 2011 – Optimising Cell Culture Development for Biopharmaceutical, Bioprocessing and Manufacture February 28-March 2, 2011 Munich, Germany 6th Annual Stem Cell Summit March 1, 2011 New York, United States American Association for Cancer Research (AACR) Stem Cells, Development, and Cancer March 3-6, 2011 Vancouver, Canada Keystone Symposia: Stem Cells, Cancer and Metastasis March 6-11, 2011 Dillon, United States PITTCON Conference & Expo 2011 March 13-18, 2011 Atlanta, United States 15th Annual Hilton Head Workshop – Regenerative Medicine, Innovations for Clinical Applications March 16-19, 2011 Hilton Head Island, United States StemCONN 11 March 22, 2011 Farmington, United States United Kingdom National Stem Cell Network 2011 Annual Scientific Conference March 30-April 1, 2011 York, United Kingdom World Stem Cells & Regenerative Medicine Congress 2011 May 9-11, 2011 London, United Kingdom Tissue Engineering & Regenerative Medicine International Society (TERMIS) – Europe 2010 Annual Conference June 7-10, 2011 Granada, Spain International Society for Stem Cell Research (ISSCR) 9th Annual Meeting June 15-18, 2011 Toronto, Canada Tissue Engineering & Regenerative Medicine International Society (TERMIS) 2011 Asia Pacific Meeting (TERMIS AP 2011) August 3-5, 2011 Singapore Adult MSC2011 Innovations in Cell-Based Regenerative Therapies August 22-24, 2011 Cleveland, United States Cell Therapy Manufacturing – Stem Cells and Immunotherapeutics December 1-2, 2011 London, United Kingdom Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Lab Technologist – Cell Separation (STEMCELL Technologies) Lab Technologist – Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies) Lab Technologist – Tissue Culture (STEMCELL Technologies) Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Mesenchymal Cell News at no cost. Visit here to post your career opportunities.
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