Cellular and Extracellular Programming of Cell Fate through Engineered Intracrine-, Paracrine-, and Endocrine-like Mechanisms Specifically, researchers show that human mesenchymal stem cells can be engineered with poly lactide-co-glycolic acid particles containing dexamethasone, which acts on cytoplasmic receptors. The controlled release properties of these particles allowed for sustained intracellular and extracellular delivery of agent to promote differentiation of particle-carrying cells, as well as neighboring cells and distant cells that do not contain particles. [Biomaterials] In Vivo Magnetic Resonance Imaging of Cell Tropsim, Trafficking Mechanism, and Therapeutic Impact of Human Mesenchymal Stem Cells in a Murine Glioma Model In this study, researchers describe the use of ferucarbotran and protamine (Fer-Pro) complexes for labeling human mesenchymal stem cells for MRI tracking of glioma tropism in vivo. [Biomaterials] The Effect of Two and Three Dimensional Cell Culture on the Chondrogenic Potential of Human Adipose-Derived Mesenchymal Stem Cells After Subcutaneous Transplantation with an Injectable Hydrogel This study aims at investigating the influence of in vitro chondrogenic differentiation of human adipose tissue-derived stem cells on in vivo cartilage formation when associated with a cellulose-based self-setting hydrogel. [Cell Transplant] Effect of Dimethyl Sulfoxide (DMSO) on Cryopreservation of Porcine Mesenchymal Stem Cells (pMSCs) Researchers compared the viability, colony forming unit-fibroblast (CFU-F) assay, expression of Bak and Bcl2 genes, Bcl2 protein antigen and CD90 in pMSCs cryopreserved with 5, 10 and 20% DMSO. [Cell Transplant] Autologous Lung-Derived Mesenchymal Stem Cell Transplantation in Experimental Emphysema Autologous lung-derived mesenchymal stem cells (LMSCs) were transplanted endoscopically into sheep with experimental emphysema to assess their capacity to regenerate functional tissue. [Cell Transplant] Chondrogenesis from Human Placenta-Derived Mesenchymal Stem Cells (hPMSCs) in 3D Scaffolds for Cartilage Tissue Engineering In this study, hPMSCs were grown in a three-dimensional (3D) environment for cartilage tissue formation in vitro. To select proper scaffolds for 3D culture of mesenchymal stem cells (MSCs), rat adipose-derived mesenchymal stem cells (rMSCs) were initially employed to optimize the composition and condition of the 3D environment. [Tissue Eng Part A] Microvascular Mural Cell Functionality of Human Embryonic Stem Cell Derived Mesenchymal Cells Researchers have developed lines of multipotent mesenchymal cells from human embryonic stem cells (hES-MC) which they hypothesize can function as perivascular mural cells. [Tissue Eng Part A] Acute Hepatic Failure-Derived Bone Marrow Mesenchymal Stem Cells Express Hepatic Progenitor Cell Genes This study aimed to determine whether bone marrow mesenchymal stem cells isolated from rats in acute hepatic failure (AHF) possess hepatic potential and/or characteristics. [Cells Tissues Organs] Schwann-like Mesenchymal Stem Cells Within Vein Graft Facilitate Facial Nerve Reegeneration and Remyelination The purpose of this study was to compare the ability of bone marrow mesenchymal stem cells (MSCs) and transdifferentiated Schwann-like MSCs in promoting transected facial nerve branches repair in a rabbit model of injury. [Brain Res] |