The Stimulation of Osteogenic Differentiation of Human Adipose-Derived Stem Cells by Ionic Products from Akermanite Dissolution via Activation of the ERK Pathway Researchers investigated the effect of the extract from akermanite, on proliferation and osteogenic differentiation of human adipose-derived stem cells. [Biomaterials] A Comparative Study of Neural and Mesenchymal Stem Cell-Based Carriers for Oncolytic Adenovirus in a Model of Malignant Glioma In this study, researchers evaluated neural stem cells and mesenchymal stem cells as cellular delivery vehicles for an oncolytic adenovirus in the context of human glioma. [Mol Pharm] Mesenchymal Stem Cell Inhibition of T-Helper 17 Differentiation is Triggered by Cell-Cell Contact and Mediated by Prostaglandin E2 via the EP4 Receptor Mesenchymal stem cell influence on the differentiation of naïve and memory CD4+ T cells toward the T-helper 17 phenotype was examined. [Eur J Immunol] Favorable Response of Chronic Refractory Immune Thrombocytopenic Purpura to Mesenchymal Stem Cells Seven patients with chronic refractory immune thrombocytopenic purpura received adipose tissue-derived mesenchymal stem cells from haplo-identical family donors. [Stem Cells Dev] Wnt/β-Catenin Signaling Induces the Aging of Mesenchymal Stem Cells through the DNA Damage Response and the p53/p21 Pathway In the current study, researchers examine the effects of old rat serum (ORS) on the aging of mesenchymal stem cells (MSC), and explore the effects and mechanisms of Wnt/β-catenin signaling on MSC aging induced by ORS treatment. [PLoS One] A Comparative Study of Induced Pluripotent Stem Cells Generated from Frozen, Stocked Bone Marrow- and Adipose Tissue-Derived Mesenchymal Stem Cells Researchers generated induced pluripotent stem cells from frozen-stocked adipose tissue-derived mesenchymal stem cells and bone marrow-derived mesenchymal stem cells and examined their biological characteristics by comparative analyses. [J Tissue Eng Regen Med] Phenotypic and Functional Characterization of Human Bone Marrow Stromal Cells in Hollow-Fibre Bioreactors Researchers show that culturing human bone marrow stromal cells in a large-scale hollow-fibre bioreactor is feasible without deleterious effects on phenotype, thus providing a platform for collecting and delivering the paracrine secretions of these cells. [J Tissue Eng Regen Med] Growth-Inhibitory Effect of Neurotrophin-3-Secreting Adipose Tissue-Derived Mesenchymal Stem Cells on the D283-MED Human Medulloblastoma Cell Line The purpose of this study was to demonstrate in vitro biological effects of neurotrophins-3 (NT-3) on medulloblastoma cells and to evaluate the growth-inhibitory effect of NT-3-secreting stem cells on tumor cells. [J Neurooncol] Cell Proliferation and Neuroblast Differentiation in the Rat Dentate Gyrus after Intrathecal Treatment with Adipose-Derived Mesenchymal Stem Cells In the present study, researchers investigated the effects of adipose-derived mesenchymal stem cell transplantation via intrathecal injection through the cisterna magna on cell proliferation and differentiation of endogenous stem cells in the hippocampal dentate gyrus using Ki-67 and doublecortin. [Cell Mol Neurobiol] Adipose-Derived Stromal Cells Cultured in a Low-Serum Medium, but not Bone Marrow-Derived Stromal Cells, Impede Xenoantibody Production The aim of this study was to compare the action of low serum-cultured adipose-derived mesenchymal stromal cells (ASC), high serum-cultured ASC, and bone marrow-derived mesenchymal stromal cell, on xenoantibody production by B cells. [Xenotransplantation] |