Nanoscale Surfaces for the Long-Term Maintenance of Mesenchymal Stem Cell Phenotype and Multipotency Researchers identify a nanostructured surface that retains stem-cell phenotype and maintains stem-cell growth over eight weeks. [Nat Mater] Enhanced Angiogenesis by Transplantation of Mesenchymal Stem Cell Sheet Created by a Novel Magnetic Tissue Engineering Method In this study, researchers investigated a therapeutic potential of mesenchymal stem cell sheet created by a novel magnetite tissue engineering technology for reparative angiogenesis. [Arterioscler Thromb Vasc Biol] Mesenchymal Stem Cells Stably Transduced with a Dominant-Negative Inhibitor of CCL2 Greatly Attenuate Bleomycin-Induced Lung Damage In this study, researchers established mesenchymal stem cells (MSCs) that are stably transduced by a lentiviral vector expressing 7ND, a dominant-negative inhibitor of CCL2, to enhance the therapeutic function of MSCs. [Am J Pathol] Purinergic Receptors Influence the Differentiation of Human Mesenchymal Stem Cells Researchers show for the first time that the combination of several P2 receptors plays a role in the differentiation of adult stem cells. [Stem Cells Dev] Spatial Organization of Mesenchymal Stem Cells In Vitro – Results from a New Individual Cell-Based Model with Podia Researchers present an individual cell-based model that is able to quantitatively describe the spatio-temporal organization of mesenchymal stem cells in culture. [PLoS One] Enhanced Mesenchymal Stromal Cell Recruitment via Natural Killer Cells by Incorporation of Inflammatory Signals in Biomaterials Researchers studied how biomaterials designed to incorporate inflammatory signals affected natural killer (NK) cell behavior and NK cell-mesenchymal stem/stromal cell interactions. [J R Soc Interface] Posterolateral Spinal Fusion with Nano-Hydroxyapatite-Collagen/PLA Composite and Autologous Adipose-Derived Mesenchymal Stem Cells in a Rabbit Model In this study, researchers analyzed the effectiveness of a new mineralized collagen matrix, nano-hydroxyapatite–collagen–polylactic acid (PLA), combined with autologous adipose-derived mesenchymal stem cells as a graft material for posterolateral spinal fusion in a rabbit model. [J Tissue Eng Regen Med] Mesenchymal Stem Cells Rescue the Alzheimer’s Disease Cell Model from Cell Death Induced by Misfolded Truncated Tau The aim of this study was to test the possible capability of rat mesenchymal stem cells to interfere with human misfolded truncated tau protein-induced cell death. [Neuroscience] Cocaine- and Amphetamine-Regulated Transcript Promotes the Differentiation of Mouse Bone Marrow-Derived Mesenchymal Stem Cells into Neural Cells This study demonstrated that cocaine- and amphetamine-regulated transcript could promote the differentiation of bone marrow mesenchymal stromal cells into neural cells through increasing neurofactors, including BNDF and NGF. [BMC Neurosci] |