Dedifferentiation-Reprogrammed Mesenchymal Stem Cells with Improved Therapeutic Potential Here researchers show that, after in vitro induction of neuronal differentiation and dedifferentiation, upon withdrawal of extrinsic factors, mesenchymal stem cells derived from bone marrow, which have already committed to neuronal lineage, revert to a primitive cell population retaining stem cell characteristics but exhibiting a reprogrammed phenotype distinct from their original counterparts. [Stem Cells] Abstract | Press Release
Human Dermis Harbors Distinct Mesenchymal Stromal Cell Subsets To shed light on the characteristics of human dermal mesenchymal stromal cells (MSCs), this study was designed to identify and isolate dermal MSCs by a specific marker expression profile, and subsequently rate their mesenchymal differentiation potential. [J Invest Dermatol] Abstract