Mesenchymal Stromal Cell Mutations and Wound Healing Contribute to the Etiology of Desmoid Tumors Researchers hypothesized that desmoid tumors may arise in familial adenomatous polyposis coli patients after mesencyhmal stromal cells acquire somatic mutations during the proliferative phase of wound healing. [Cancer Res] Abstract Synergistic Control of Mesenchymal Stem Cell Differentiation by Nanoscale Surface Geometry and Immobilized Growth Factors on TiO2 Nanotubes The aim of this study is to elucidate whether combined environmental signals provided by nanoscale topography and by growth factors control cell behavior of mesenchymal stem cells in a synergistic or simply additive manner. [Small] Abstract ß-PIX Is Critical for Transplanted Mesenchymal Stromal Cell Migration Researchers suggest that transplantation of allogeneic or genetically modified autologous stem cells might be a more promising strategy for amyotrophic lateral sclerosis patients than transplantation of autologous stem cells. [Stem Cells Dev] Abstract Differential Signaling through ALK-1 and ALK-5 Regulates Leptin Expression in Mesenchymal Stem Cells Here, researchers investigated leptin expression in mesenchymal stem cells from bone marrow and cord matrix. [Stem Cells Dev] Abstract Differentiation of Induced Pluripotent Stem Cells into Dental Mesenchymal Cells Here researchers demonstrated that neural crest-like cells derived from mouse induced pluripotent stem cells have the potential to differentiate into odontogenic mesenchymal cells. [Stem Cells Dev] Abstract Modulation of Human Mesenchymal Stem Cell Function in a Three-Dimensional Matrix Promotes Attenuation of Adverse Remodeling after Myocardial Infarction Researchers hypothesized that human mesenchymal stem cells applied to the heart in a collagen matrix would outperform the same cells grown in a monolayer and directly injected for cardiac cell replacement after myocardial infarction in a rat model. [J Tissue Eng Regen Med] Abstract Cartilage Oligomeric Matrix Protein Enhances Matrix Assembly during Chondrogenesis of Human Mesenchymal Stem Cells To test the hypothesis that cartilage oligomeric matrix protein (COMP)/thrombospondin-5 functions in the assembly of the extracellular matrix during cartilage morphogenesis, researchers have employed mesenchymal stem cell chondrogenesis in vitro as a model to examine the effects of COMP over-expression on neo-cartilage formation. [J Cell Biochem] Abstract Analysis of the Effects of HIV-1 Tat on the Survival and Differentiation of Vessel Wall-Derived Mesenchymal Stem Cells As vessel wall mesenchymal stem cells (MSCs) are involved in the regulation of vessel structure homeostasis, researchers investigated the role of Tat, a key factor in HIV replication and pathogenesis, in MSC survival and differentiation. [J Cell Biochem] Abstract |