Bone Marrow-Derived Human Mesenchymal Stem Cells Express Cardiomyogenic Proteins but Do Not Exhibit Functional Cardiomyogenic Differentiation Potential To systematically evaluate the role of differentiation in mesenchymal stem cell (MSC)-mediated cardiac regeneration, the cardiomyogenic differentiation potential of human MSCs and murine MSCs was investigated in vitro and in vivo by inducing cardiomyogenic and non-cardiomyogenic differentiation. [Stem Cells Dev] Abstract Primary Involvement of NADPH Oxidase 4 in Hypoxia-Induced Generation of Reactive Oxygen Species in Adipose-Derived Stem Cells Researchers sought to investigate which subtype of NADPH oxidase (Nox) is primarily expressed in adipose-derived stem cells (ASCs), where Nox4 is localized in ASCs and whether silencing of Nox4 attenuates hypoxia-enhanced function of ASC. [Stem Cells Dev] Abstract Mesenchymal Stem Cell-Conditioned Media Recovers Lung Fibroblasts from Cigarette Smoke-Induced Damage In this study researchers attempted to determine whether mesenchymal stem cell-conditioned media can recover lung fibroblasts from cigarette smoke-induced damage. [Am J Physiol Lung Cell Mol Physiol] Abstract Mesenchymal Stromal Cells Improve the Osteogenic Capabilities of Mineralized Agarose Gels in a Rat Full-Thickness Cranial Defect Model Mesenchymal stromal cells (MSCs) have osteogenic potential and are considered useful for bone tissue engineering. The purpose of this study was to clarify the osteogenic abilities of MSCs loaded in HAp or CaCO3 gels using a rat cranial defect model compared to HAp and CaCO3 gels alone. [J Tissue Eng Regen Med] Abstract Bone Tissue Engineering using Bone Marrow Stromal Cells and an Injectable Sodium Alginate/Gelatin Scaffold Researchers investigate the potential application of bone marrow stromal cells and an injectable sodium alginate/gelatin scaffold for bone tissue engineering. [J Biomed Mater Res A] Abstract Canine Bone Marrow Mesenchymal Stromal Cells with Lentiviral mHCN4 Gene Transfer Create Cardiac Pacemakers Researchers’ aim was to test the ability of canine mesenchymal stromal cells transfected with the mouse hyperpolarization-activated cyclic nucleotide-gated channel 4 (mHCN4) gene to deliver a biologic pacemaker to the canine heart. [Cytotherapy] Abstract Basic Fibroblast Growth Factor Modulates Cell Cycle of Human Umbilical Cord-Derived Mesenchymal Stem Cell This study has aimed to establish optimum conditions to generate and characterize mesenchymal stem cells (MSC) from human umbilical cord. [Cell Prolif] Abstract |