Mesenchymal Stem Cell Secreted Platelet Derived Growth Factor Exerts a Pro-Migratory Effect on Resident Cardiac Atrial Appendage Stem Cells The authors aimed to test the pro-migratory effect of mesenchymal stem cell conditioned medium on endogenous cardiac stem cells from human cardiac tissue. [J Mol Cell Cardiol] Abstract Treatment of Graft versus Host Disease with Mesenchymal Stromal Cells: A Phase I Study on 40 Adult and Pediatric Patients This Phase I multicenter study aimed at assess the feasibility and safety of intravenous administration of third party-bone marrow derived mesenchymal stromal cells expanded in platelet lysate in 40 patients, experiencing steroid-resistant grade II-IV graft versus host disease. [Biol Blood Marrow Transplant] Abstract Mechano Growth Factor E Peptide Regulates Migration and Differentiation of BMSCs Scientists investigated on the effects of mechano growth factor (MGF) E peptide on bone marrow mesenchymal stem cells (BMSCs). Their results revealed that cells treated with MGF E peptide didn’t affect proliferation. [J Mol Endocrinol] Abstract Novel Therapy for Insulin-Dependent Diabetes Mellitus: Infusion of In Vitro-Generated Insulin-Secreting Cells Researchers present their experience of treating insulin-dependent diabetes mellitus with co-infusion of in vitro autologous adipose tissue-derived mesenchymal stem cells-differentiated insulin-secreting cells with hematopoietic stem cells. [Clin Exp Med] Abstract Cytocompatibility Evaluation of Different Biodegradable Magnesium Alloys with Human Mesenchymal Stem Cells Eight different magnesium alloys containing varying amounts of Al, Zn, Nd and Y were either incubated directly or indirectly with the osteosarcoma cell line Saos-2 or with uninduced and osteogenically-induced human mesenchymal stem cells isolated from bone marrow specimens obtained from the femoral shaft of patients undergoing total hip replacement. [J Mater Sci Mater Med] Abstract Pre- and Postnatal Transplantation of Fetal Mesenchymal Stem Cells in Osteogenesis Imperfecta: A Two-Center Experience Investigators report the clinical course of two patients with osteogenesis imperfecta who received prenatal human fetal mesenchymal stem cells (MSC) transplantation and postnatal boosting with same-donor MSCs. [Stem Cells Transl Med] Abstract | Press Release Sox2 Suppression by miR-21 Governs Human Mesenchymal Stem Cell Properties Scientists analyzed the microRNA (miRNA) profile of mesenchymal stem cells (MSCs) derived from amniotic fluid, bone marrow, and umbilical cord blood. They initially identified 67 different miRNAs that were expressed in all three types of MSCs but at different levels, depending on the source. [Stem Cells Transl Med] Abstract |