 | | Vol. 5.35 – 5 October, 2020 |
| |
|
|
| The use of recombinant human tropoelastin as a highly biocompatible and elastic bioink for 3D printing of complex soft tissues was demonstrated. As proof of the concept, vascularized cardiac constructs were bioprinted and their functions were assessed in vitro and in vivo.
[Advanced Materials] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
| |
|
|
| Investigators optimized and validated a new Single-Cell Western method to assess protein expression in human induced pluripotent stem cell-derived cardiomyocytes.
[Journal of Molecular and Cellular Cardiology] |
|
|
|
| Fibroblast-conditioned media (fCM)-mediated response seemed to be spatially-dependent as cardiomyocyte organoids treated with fCM had increased expression of connexin 40 and NAV1.5 primarily on its outer surface.
[Scientific Reports] |
| |
|
|
| Scientists compared skeletal muscle sarcopenia in a novel two‐stage model of right ventricular failure to an established model of left ventricular failure.
[Journal of Cachexia Sarcopenia and Muscle] |
|
|
|
| By isolating adult myofibres with associated muscle stem cells investigators found that myog-/- myofibres have severely reduced nuclear number, but increased myonuclear domain size.
[eLife] |
|
|
|
| Researchers determined if m6A-modification deposition via METTL3 is a regulator of muscle-specific adult stem cell/myoblast state transitions in vitro and in vivo.
[Cell Death Discovery] |
| |
|
|
| Using three complementary mouse models of carotid artery injury, researchers demonstrated that both tamoxifen and estradiol accelerated endothelial healing, but only tamoxifen required the presence of the underlying medial smooth muscle cells.
[Circulation Research] |
|
|
|
| Prior to extrusion, the innermost cell encapsulating hydrogel was loaded with HUVECs, whereas the outer hydrogel was loaded with human aortic smooth muscle cells.
[Biofabrication] |
|
|
|
| Scientists report that reduction of microRNA-27a-3p causes an increase in ATF3, activating transcription factor 3, a novel osteogenic transcription factor, in vascular smooth muscle cells.
[Molecular Therapy-Nucleic Acids] |
|
|
|
| The authors explored the circular RNA profile in pulmonary arterial hypertension patients caused by chronic obstructive pulmonary disease and the effects of hsa_circNFXL1_009 on abnormal proliferation, apoptosis, and migration of human pulmonary arterial smooth muscle cells driven by hypoxia.
[Molecular Therapy-Nucleic Acids] |
|
|
|
|
| The authors briefly survey cell sources and delivery strategies, along with biomaterials and their processing techniques, developed for myocardial infarction treatment. Key issues and challenges, as well as recommendations for future research, are also discussed.
[Advanced Healthcare Materials] |
|
|
|
|
| Pfizer Inc. announced that its investigational gene therapy candidate being developed to treat Duchenne muscular dystrophy received Fast Track designation from the FDA.
[Pfizer Inc.] |
|
|
|
|
| April 9 – April 14, 2021
Washington, DC, United States |
|
|
|
|
|
| | Beth Israel Deaconess Medical Center – Boston, Massachusetts, United States |
|
|
|
| | University of Luxembourg – Luxembourg, Luxembourg |
|
|
|
| | University of Vermont – Burlington, Vermont, United States |
|
|
|
| | University of California, Davis – Davis, California, United States |
|
|
|
| | University of North Carolina at Chapel Hill – Chapel Hill, North Carolina, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
