| Vol. 6.34 – 4 October, 2021 |
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| Scientists found that the majority of cycling cardiomyocytes were positioned in the subendocardial muscle of the left ventricle, especially in the papillary muscles [Nature Communications] |
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PUBLICATIONSRanked by the impact factor of the journal |
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| Researchers found that the level of mmu_circ_000338, a cardiac- necroptosis-associated circRNA, was reduced in hypoxia-reoxygenation exposed cardiomyocytes and ischemia-reperfusion-injured mice hearts. [Cell Death & Disease] |
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| Scientists employed MHY-1685, a novel mammalian target of rapamycin inhibitor, and examined its long-term priming effect on the activities of senile human cardiac stem cells (hCSCs) and the functional benefits of primed hCSCs after transplantation. [Experimental and Molecular Medicine] |
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| The down-regulation of cell cycle genes and the up-regulation of the mature myofilament genes in cardiomyocytes in vitro (iCMs) reached intermediate levels between those of fetal and neonatal cardiomyocytes. Cardiomyo-miRs were up-regulated in iCMs. [Communications Biology] |
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| Mesenchymal stem cell (MSC) aggregation into spheroids was optimized in vitro based on cellular viability, spheroid size, and trophic factor secretion. The regenerative potential of the optimized MSC spheroid therapy was then investigated in a murine model of volumetric muscle loss injury. [Tissue Engineering and Regenerative Medicine] |
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| Researchers investigated the mechanisms by which pathological changes in the microvasculature direct fibrosis in the context of ischemia-reperfusion. [Biochimica Et Biophysica Acta-Molecular Basis of Disease] |
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| USP10 expression was detected in mouse arteries and increased after carotid ligation. In vitro data showed that USP10 deficiency reduced proliferation and migration of rat thoracic aorta smooth muscle cells and human aortic smooth muscle cells. [Journal of Biological Chemistry] |
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| Investigators found that lncRNA XIST was related to the abnormal proliferation and migration of human vascular smooth muscle cells (HVSMCs), and thus, the mechanism by which XIST regulated HVSMCs was further investigated. [Kaohsiung Journal of Medical Sciences] |
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| The apoptosis of smooth muscle cells is a major feature of thoracic aortic aneurysm. Scientists investigated the roles of circ_0091434 in human aortic smooth muscle cells. [Human Pathology] |
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| The expression of genes MYF5, MRF4, MYOD is activated by muscle progenitors throughout development, in several waves of myogenic differentiation, constituting the embryonic, fetal and postnatal phases of muscle growth. [Cell Regeneration] |
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| Baxter International, Inc. announced the US FDA approval and commercial launch of premix Norepinephrine Bitartrate in 5% Dextrose Injection. [Baxter International, Inc.] |
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| October 26 – 28, 2021 Virtual |
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| Radboud University Medical Centre – Nijmegen, Netherlands |
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| Harvard Medical School – Boston, Massachusetts, United States |
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| Queen’s University Belfast – Belfast, Ireland |
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| Sanford Burnham Prebys Medical Discovery Institute – San Diego, California, United States |
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| European Centre Study Diabetes – Strasbourg, France |
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