 | | Vol. 14.27 – 22 July, 2020 |
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| Investigators tested remapping in amyloid precursor protein knockin mice with impaired spatial memory. CA1 neurons, including place cells, showed disrupted remapping, although their spatial tuning was only mildly diminished.
[Neuron] |
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 | | PUBLICATIONSRanked by the impact factor of the journal |
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| Scientists performed extensive multiomic analyses to identify an OTX2 regulatory network that controlled Group 3 medulloblastoma cell fate.
[Nature Communications] |
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| Researchers demonstrated that a label-free and noninvasive single-cell Raman microspectroscopy platform was able to identify neural cell lineages derived from clinically relevant human induced pluripotent stem cells.
[Proceedings of the National Academy of Sciences of the United States of America] |
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| Investigators elucidated a MYC-miRNA-MXI1 feedback loop that regulates proliferation and tumorigenesis in glioma.
[Cancer Research] |
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| Researchers explored the mechanisms underlying axon growth in three dimensions. They found that CNS neurons used amoeboid mechanisms to drive axon growth.
[Cell Reports] |
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| The authors identified distinct transcript changes in individual Piezo2-expressing mechanosensitive dorsal root ganglia neurons by combining electrophysiology with single-cell RNA sequencing.
[Cell Reports] |
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| Researchers showed that hippocampal cells contained a diverse collection of over 70 CaMKII transcripts from all four CaMKII-encoding genes.
[Science Signaling] |
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| The authors developed a weakly supervised deep learning segmentation approach of fluorescence nanoscopy images of F-actin in cultured hippocampal neurons.
[Scientific Reports] |
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| Scientists investigated the role of the developmental mitogen sonic hedgehog in initiating carcinogenesis in the cells of origin: granule cell progenitors
[Nature Cancer] |
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| The authors describe how satellite glial cells are altered in rodent models of four common types of pain: systemic inflammation, post-surgical pain, diabetic neuropathic pain and post-herpetic pain.
[Nature Reviews Neuroscience] |
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| CytRx Corporation highlighted Orphayzme A/S’s announcement that it will join The Michael J. Fox Foundation’s Parkinson’s Disease Research Tools Consortium.
[CytRx Corporation] |
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| Banner Life Sciences LLC announced that BAFIERTAM™, a novel fumarate for adults for the treatment of relapsing forms of multiple sclerosis, including clinically isolated syndrome, relapsing-remitting disease, and active secondary progressive disease, will be commercially available in the US.
[Banner Life Sciences ] |
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| A historic €1.8-trillion (US$2.1-trillion) budget deal reached by European Union (EU) leaders to fund its next seven years — and its recovery from the coronavirus pandemic — has left scientists and research advocates disappointed.
[Nature News] |
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| | The Chinese University of Hong Kong – Hong King, China |
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| | Simon Fraser University – Burnaby, British Columbia, Canada |
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| | BrightFocus Foundation – Clarksburg, Maryland, United States |
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| | Klinikum rechts der Isar of the Technische Universität München – Munich, Germany |
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| | NIH National Institute of Mental Health – Bethesda, Maryland, United States |
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