 | | Vol. 16.22 – 8 June, 2022 |
| |
|
|
| Scientists carried out extensive characterizations of tau isoforms expressed in human neurons derived by microRNA-induced neuronal reprogramming of adult fibroblasts.
[Cell Stem Cell] |
|
|
|
 | | PUBLICATIONSRanked by the impact factor of the journal |
|
|
|
| Co-culture assays followed by Cell Counting Kit-8, migration, Matrigel tube formation, and sprouting assays were conducted to assess the proliferative, migratory, and angiogenic capacity of glioblastoma multiforme cells and human brain microvascular endothelial cells.
[Molecular Psychiatry] |
|
|
|
| Researchers reported that in both stem cell-derived human neurons as well as in vivo mouse neurons of purely glutamatergic identity, ectopic expression of GABA-synthesis enzymes and vesicular transporters were sufficient to both produce GABA from ambient glutamate and transmit it from presynaptic terminals.
[Nature Communications] |
|
|
|
| The authors reported that pharmacologic targeting of methyltransferase-like 3 augmented anti-tumor efficacy of platelet-derived growth factor receptor (PDGF) and mitophagy inhibitors in vitro and in vivo.
[Developmental Cell] |
|
|
|
| Glioblastoma-associated microglia M2 polarization was constructed, and microglia-derived exosomes were isolated to co-culture with human brain microvessel endothelial cells.
[Oncogene] |
|
|
|
| Researchers presented a microfluidic model of vascularized glioblastoma featuring a tumor spheroid in direct contact with self-assembled vascular networks comprising human endothelial cells, astrocytes, and pericytes.
[Proceedings of the National Academy of Sciences of the United States of America] |
|
|
|
| Scientists investigated the effects associated with snail family transcriptional repressor 2 (SNAI2) on the proliferation of glioma stem cells to elucidate its underlying molecular mechanism in the development of glioma.
[Cell Death & Disease] |
|
|
|
| Investigators reported that inhibitors of apoptosis, necroptosis, and ferroptosis exhibited marked retinal ganglion cells (RGC) protection against ischemia reperfusion both in mice and primary cultured RGCs.
[Cell Death & Disease] |
|
|
|
| Scientists reported that patient-derived motoneurons and ganglioside-induced differentiation-associated protein 1 (GDAP1) knockdown SH-SY5Y cells displayed two phenotypes: more tubular mitochondria and a metabolism characterized by glutamine dependence and fewer cytosolic lipid droplets.
[Communications Biology] |
|
|
|
|
| The authors discuss recent advances in induced pluripotent stem cell technology that have made it possible to generate patient-derived dopaminergic neuronal cell culture and organoid models of Parkinson’s disease.
[Trends in Neurosciences] |
|
|
|
| Scientists provide an updated overview of the recent discoveries and advancements on mitophagic molecular dysfunctions in Alzheimer’s disease (AD)-derived fluids and cells as well as in AD brains.
[Molecular Psychiatry] |
|
|
|
|
| Albert Einstein College of Medicine researchers have been awarded a five-year, $3.5 million grant from the National Institutes of Health (NIH) to study the effects of COVID-19 on the brains of adults who had mild or asymptomatic infection.
[Albert Einstein College of Medicine] |
|
|
|
|
| September 7 – 11, 2022
Woods Hole, Massachusetts, United States |
|
|
|
|
|
| | German Cancer Research Center in the Helmholtz Association – Heidelberg, Germany |
|
|
|
| | La Jolla Institute for Immunology – La Jolla, California, United States |
|
|
|
| | Flanders Institute for Biotechnology – Leuven, Belgium |
|
|
|
| | The University of British Columbia – Vancouver, British Columbia, Canada |
|
|
|
| | The University of Chicago – Chicago, Illinois, United States |
|
|
|
|
Cancer Stem Cell News
Cell Therapy News
Dermal Cell News
Endothelial Cell News
ESC & iPSC News
Extracellular Matrix News
Hematopoiesis News
Hepatic Cell News
Human Immunology News
Immune Regulation News
Intestinal Cell News
Mammary Cell News
Mesenchymal Cell News
Muscle Cell News
Neural Cell News
Organoid News
Pancreatic Cell News
Prostate Cell News
Pulmonary Cell News
