TOP STORY New Gene Mutation Reveals New Cause of Rare Neurological Diseases Researchers at St George’s, University of London have found a gene mutation mechanism that causes a new type of defect in mitochondria. [Press release from St George’s University of London discussing online prepublication in The American Journal of Human Genetics]
| | | | | *Piccirillo et al., Nature, 2006. *Gallia et al., Mol Cancer Ther, 2009. | *McGillicuddy et al., Cancer Cell, 2009. *Zheng et al., Cancer Cell, 2010. |
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SPECIAL FEATURE Follow us on Twitter! @NeuralCell
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SCIENCE NEWS Gene Therapy May Be Powerful New Treatment for Major Depression Researchers say animal and human data suggest gene therapy to the brain may be able to treat patients with major depression who do not respond to traditional drug treatment. [Press release from Weill Cornell Medical College discussing online prepublication in Science Translational Medicine] Neurons Work Like a Chain of Dominos to Control Action Sequences By studying the brain circuits that control bird song, researchers have identified a “chain reaction” of brain activity that appears to control the timing of song. [Press release from McGovern Institute for Brain Research at Massachusetts Institute of Technology discussing online prepublication in Nature] Stem Cell Model Breakthrough for Brain Disease Research A research team reported on a new cell model they have developed to investigate brain diseases based on patient-derived stem cells. [Press release from Griffith University discussing online prepublication in Disease Models and Mechanisms] | | | | | | |
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INDUSTRY NEWS NeuroVive and to-BBB to Jointly Develop Therapy for Stroke NeuroVive Pharmaceutical AB and to-BBB are entering into a joint program to develop therapies for stroke and other acute neurodegenerative diseases by combining their technologies. [NeuroVive Pharmaceutical AB Press Release] Intellect Neurosciences, Inc. Obtains OX1 Phase Ib Draft Report Showing the Company’s Lead Alzheimer’s Candidate Was Safe and Well-Tolerated at All Dose Levels Tested Intellect Neurosciences, Inc. announced that it has obtained an initial draft report of the Company’s Phase Ib clinical trial for its lead Alzheimer’s candidate, OXIGON™ (OX1). [Intellect Neurosciences, Inc. Press Release] New Analysis of CAMBIA™ Pivotal Data to Be Presented at the 4th World Congress on Controversies in Neurology Nautilus Neurosciences, Inc. announced that an analysis of two pivotal safety and efficacy studies of CAMBIA™ (diclofenac potassium for oral solution) will be presented at the 4th World Congress on Controversies in Neurology Conference in Barcelona, Spain. [Nautilus Neurosciences, Inc. Press Release] NeurAxon’s NXN-188 Named One of 10 Most Promising Neuroscience Projects by Windhover NeurAxon, Inc. announced that NXN-188 has been selected as one of the Top 10 most promising neuroscience projects currently available for strategic partnering. [NeurAxon Inc. Press Release] MediciNova’s MN-166 Program Recognized as One of Windhover’s Top 10 Neuroscience Projects to Watch MediciNova Inc. announced that its novel macrophage migration inhibitory factor (MIF inhibitor) MN-166 program has been selected for inclusion on Windhover’s list of the “Top 10 Most Interesting Neuroscience Projects to Watch.” [MediciNova Inc. Press Release] Barrow Expanding Fight vs. Cancer Barrow Neurological Institute of Phoenix is launching a new research center aimed at battling the deadliest of brain cancers. [Barrow Neurological Institute Press Release] State Awards the University of California, Los Angeles Stem Cell Researchers $10.4M to Develop New Therapies for Disease California’s state stem cell agency has awarded grants totaling $10.4 million to four researchers at the Eli and Edythe Broad Center of Regenerative Medicine and Stem Cell Research at the University of California, Los Angeles to translate basic science into new and more effective therapies to regenerate bone, target deadly brain cancers and treat corneal disorders that result in blindness. [University of California, Los Angeles, United States] Buck Institute Awarded $6 Million to Lead Effort to Get Stem Cell Treatment for Parkinson’s Disease Ready for Clinical Trials The Buck Institute for Age Research has been awarded $6 million from the California Institute for Regenerative Medicine to fund a three-year project aimed at getting a stem cell derived treatment for Parkinson’s disease ready for testing in humans. [Buck Institute for Age Research, United States] $1,820,000 from National Science Foundation Awarded to Rutgers University, Newark, to Acquire fMRI Dedicated to Research The National Science Foundation has awarded Rutgers University in Newark a $1,820,000 grant to acquire the Siemens Trio 3T MRI scanner. [Rutgers University, United States] Center for Neuroscience Awarded $5.5 Million from National Institutes of Health to Develop Core Research Facilities The Center for Neuroscience has received grant funding of over $5.5 million from the National Institutes of Health to be disbursed over the next five years. This grant will support new state of the art core resource technologies, fund collaborative scientific pilot projects, and create several new positions at the Health Science Center. [West Virginia University Center for Neuroscience, United States]
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POLICY NEWS
Just a Flesh Wound? U.K. Science Budget Spared Deep Cuts The U.K. government’s long-awaited Comprehensive Spending Review was released, and it calls for a flat science budget over the next 4 years. While inflationary costs mean that the budget will likely see a cut of about 10% in real terms over that period, this scenario is far less dramatic than rumored cuts of 20% to 30% in real cash. [HM Treasury, United Kingdom] National Institute of Neurological Disorders amd Stroke Diversity Research Education Grants in Neuroscience (R25) (PAR-11-010)[National Institute of Neurological Disorders and Stroke, United States] National Institute of Neurological Disorders and Stroke; Notice of Closed Meeting (FR Doc. 2010-26932) [National Institute of Neurological Disorders and Stroke, United States] 2010 Meeting Materials, Transmissible Spongiform Encephalopathies Advisory Committee [Center for Biologics Evaluation and Research, United States] Guidance for Industry: Qualification Process for Drug Development Tools [Food and Drug Administration, United States] Agency Information Collection Activities; Submission for Office of Management and Budget Review; Comment Request; Current Good Manufacturing Practice Quality System Regulations (Docket No. FDA-2010-N-0273) [Food and Drug Administration, United States] Meeting Highlights from the Committee for Medicinal Products for Human Use (CHMP), 18-21 October 2010 [European Medicines Agency, European Union]
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EVENTS (Listed by Date) Fraunhofer Life Science Symposium 2010 October 29-30, 2010 Leipzig, Germany Stem Cell Society Singapore Symposium 2010: Translating Science to Therapy November 2-3, 2010 Singapore City, Singapore Joint Meeting of the Peripheral and Central Nervous System Drugs Advisory Committee and Drug Safety and Risk Management Advisory Committee Meeting November 3, 2010 Washington, D.C., United States Ninth Annual AACR International Conference on Frontiers in Cancer Prevention Research November 7-10, 2010 Philadelphia, United States International Forum on Stem Cells November 12-13, 2010 Tianjin, Peoples Republic of China 40th Annual Meeting of the Society for Neuroscience 2010 November 13-17, 2010 San Diego, United States Stem Cell Network 10th Annual Scientific Meeting November 22-24, 2010 Calgary, Canada The American Society for Cell Biology 50th Annual Meeting December 11-15, 2010 Philadelphia, United States Keystone Symposia: Adult Neurogenesis January 9-14, 2011 Taos, New Mexico Select Biosciences 5th Annual Stem Cells World Congress January 24-25, 2011 San Diego, United States Phacilitate 7th Annual Cell & Gene Therapy Forum 2011 January 24-26, 2011 Washington, DC, United States Keystone Symposia – Stem Cells in Development, Tissue Homeostasis and Disease January 30-February 4, 2011 Santa Fe, United States Neurodegenerative Diseases: The Molecular and Cellular Basis for Neurodegeneration February 21-26, 2011 Taos, United States Trends in Central Nervous System Malignancies March 25-26, 2011 Bucharest, Romania Wiring the Brain: Making Connections April 12-15, 2011 Powerscourt, Ireland Visit our events page to stay up to date with the latest events in the cell, gene and immunotherapy community. JOB OPPORTUNITIES Lab Technologist — Human Embryonic and Induced Pluripotent Stem Cells (STEMCELL Technologies) Lab Technologist — Tissue Culture (STEMCELL Technologies) Product Manager — Pluripotent Stem Cells (STEMCELL Technologies) Recruit Top Talent Reach more than 11,000 potential candidates by posting your organization’s career opportunities with Neural Cell News at no cost. Visit here to post your career opportunities.
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